Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 20/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3213850 | 0.96 | HSD11B1 (0.78) | HSD11B1 | |
| SCHEMBL5327380 | 0.88 | HSD11B1 (0.70) | HSD11B1 | |
| SCHEMBL5360560 | 0.85 | HSD11B1 (0.62) | HSD11B1 | |
| SCHEMBL3218052 | 0.82 | HSD11B1 (0.66) | HSD11B1 | |
| SCHEMBL3608843 | 0.81 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL3210183 | 0.80 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL3212651 | 0.80 | HSD11B1 (0.67) | HSD11B1 | |
| SCHEMBL3222429 | 0.79 | HSD11B1 (0.56) | HSD11B1 | |
| SCHEMBL3215217 | 0.79 | HSD11B1 (0.72) | HSD11B1 | |
| SCHEMBL3224595 | 0.79 | HSD11B1 (0.66) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007122411-A1 | DIAZEPAN-1-YL-SULFONYL DERIVATIVES FOR THE TREATMENT OF METABOLIC SYNDROME | ASTRAZENECA AB (SE) | 2007-11-01 | — | — | WO | disclosed |