Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 9/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | SPR | P35270 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5451245 | 0.74 | MEN1 (0.42) | HPGDNPC1ALDH1A1POLBMEN1 | |
| SCHEMBL2558780 | 0.70 | HPGD (0.46) | HPGDNPC1GLAALDH1A1HSD11B1 | |
| SCHEMBL5643525 | 0.70 | HSD11B1 (0.40) | HPGDNPC1ALDH1A1HSD11B1 | |
| SCHEMBL8541103 | 0.68 | HPGD (0.42) | HPGDNPC1GLAALDH1A1POLB | |
| SCHEMBL21650204 | 0.65 | HPGD (0.58) | HPGDNPC1GLAALDH1A1HSD11B1 | |
| SCHEMBL29944043 | 0.63 | HSD11B1 (0.66) | HPGDNPC1GLAALDH1A1HSD11B1 | |
| SCHEMBL3455787 | 0.63 | HPGD (0.80) | HPGDNPC1GLAALDH1A1POLB | |
| SCHEMBL11112400 | 0.63 | HPGD (0.80) | HPGDNPC1GLAALDH1A1POLB | |
| SCHEMBL3456204 | 0.63 | HSD11B1 (0.66) | HPGDNPC1GLAALDH1A1HSD11B1 | |
| SCHEMBL7132525 | 0.62 | HPGD (1.00) | HPGDALDH1A1TSHRUSP2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070276016-A1 | BENZO[1,2,5]THIADIAZOLE COMPOUNDS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070276016-A1 | BENZO[1,2,5]THIADIAZOLE COMPOUNDS | CCKBR, CCKAR, GIPR | HPGD 1693/4885NPC1 1643/4885GLA 4755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.