Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1269730 | 0.94 | POLB (0.45) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL16243654 | 0.89 | POLB (0.49) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL1020562 | 0.88 | HTT (0.51) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL1535487 | 0.78 | HTT (0.57) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL16243613 | 0.78 | POLB (0.37) | POLBAPEX1HTTTDP1ALDH1A1 | |
| SCHEMBL29052705 | 0.77 | POLB (0.49) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL2787758 | 0.76 | POLB (0.52) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL17800992 | 0.75 | POLB (0.51) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL5525853 | 0.75 | ALDH1A1 (0.34) | POLBAPEX1HTTTDP1ALDH1A1 | |
| SCHEMBL12394952 | 0.74 | POLB (0.47) | THRBPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8110625-B2 | Rubber composition | BRIDGESTONE CORPORATION (JP) | 2012-02-07 | — | — | US | disclosed |
| US-20100298488-A1 | RUBBER COMPOSITION | BRIDGESTONE CORPORATION (JP) | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298488-A1 | RUBBER COMPOSITION | RAD50, RAD54L, VCL | THRB 3667/4885POLB 613/4885APEX1 1618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.