Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.30 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL544072 | 0.94 | THRB (0.43) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL16243654 | 0.92 | POLB (0.49) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL1020562 | 0.91 | HTT (0.51) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL1535487 | 0.83 | HTT (0.57) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL29052705 | 0.83 | POLB (0.49) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL16243613 | 0.81 | POLB (0.37) | POLBAPEX1HTTTDP1ALDH1A1 | |
| SCHEMBL1270061 | 0.80 | THRB (0.44) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL5175653 | 0.80 | THRB (0.42) | THRBTSHRALDH1A1 | |
| SCHEMBL36344 | 0.80 | POLB (0.43) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL33455 | 0.79 | THRB (0.45) | POLBAPEX1HTTTDP1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100098762-A1 | Thermosensitive Pluronic Derivative Hydrogels With High Biodegradability And Biocompatibility For Tissue Regeneration And Preparation Method Thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2010-04-22 | — | — | US | claimed |
| WO-2007064152-A1 | INJECTABLE THERMOSENSITIVE PLURONIC HYDROGELS COUPLED WITH BIOACTIVE MATERIALS FOR TISSUE REGENERATION AND PREPARATION MEHTOD THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2007-06-07 | — | — | WO | claimed |
| US-6858164-B2 | Silicone-oil soluble polymer, image display medium using the silicone-oil soluble polymer and image display device using the image display medium | RICOH COMPANY LIMITED (JP) | 2005-02-22 | — | — | US | claimed |
| US-6765713-B2 | STABLE DISPERSION OF SILICONE OIL SOLUBLE POLYMER AND ORGANIC SULFONIC ACID COMPONENT | RICOH COMPANY, LTD. (JP) | 2004-07-20 | — | — | US | claimed |
| US-20030230487-A1 | Electrophoretic composition, image display medium using same and image display device | TRANSCEND OPTRONICS (YANGZHOU) CO., LTD. (CN) | 2003-12-18 | — | — | US | claimed |
| EP-0425200-A1 | Bone cement composition, cured product thereof, implant material and process for the preparation of the same | NOBUO NAKABAYASHI (JP) | 1991-05-02 | — | — | EP | claimed |
| EP-0252603-A2 | Adhesives for ceramics and processes for the bonding of ceramics using same | MITSUI SEKIYU KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-01-13 | — | — | EP | claimed |
| US-12091537-B2 | Composition and molded article containing fluorine-containing polymer | DAIKIN INDUSTRIES, LTD. (JP) | 2024-09-17 | — | — | US | disclosed |
| CN-118139941-A | Adhesive composition | 株式会社力森诺科 | 2024-06-04 | — | — | CN | disclosed |
| WO-2023068302-A1 | ADHESIVE COMPOSITION | 株式会社レゾナック | 2023-04-27 | — | — | WO | disclosed |
| CN-112513175-B | Fluoropolymer-containing composition and molded article | 大金工业株式会社 | 2023-02-21 | — | — | CN | disclosed |
| US-20210317295-A1 | COMPOSITION AND MOLDED ARTICLE CONTAINING FLUORINE-CONTAINING POLYMER | DAIKIN INDUSTRIES, LTD. (JP) | 2021-10-14 | — | — | US | disclosed |
| WO-2021160788-A1 | METHODS FOR REDUCING OR PREVENTING COLLOIDS ADHESION AND/OR FOULING ON DIFFERENT SUBSTRATES, COMPOSITIONS, AND COPOLYMERS USEFUL THEREFOR | SOLVAY SA (BE) | 2021-08-19 | — | — | WO | disclosed |
| US-5047442-A | Photopolymerizable composition based on a vinyl compound, a sulfur-containing compound and an alpha-diketone | MITSUBISHI RAYON COMPANY LIMITED (JP) | 1991-09-10 | — | — | US | disclosed |
| EP-0173290-B1 | COMPOSITIONS FOR ARTIFICIAL MARBLES AND PROCESS FOR PRODUCING ARTIFICIAL MARBLES THEREFROM | MITSUBISHI RAYON CO., LTD. (JP) | 1991-07-10 | — | — | EP | disclosed |
| EP-0401385-A1 | DENTAL COMPOSITION AND PROCESS FOR PREPARING HIGH-MOLECULAR SHAPE FOR DENTAL USE | MITSUBISHI RAYON CO., LTD. (JP) | 1990-12-12 | — | — | EP | disclosed |
| US-4826888-A | STORAGE STABLE, DISCOLORATION INHIBITION | MITSUBISHI RAYON CO., LTD. (JP) | 1989-05-02 | — | — | US | disclosed |
| US-4777190-A | Photopolymerizable composition based on a vinyl compound, a sulfur-containing compound and an α-diketone | MITSUBISHI RAYON COMPANY LIMITED (JP) | 1988-10-11 | — | — | US | disclosed |
| EP-0201903-A2 | Photopolymerizable composition | MITSUBISHI RAYON CO., LTD. (JP) | 1986-11-20 | — | — | EP | disclosed |
| EP-0173290-A2 | Compositions for artificial marbles and process for producing artificial marbles therefrom | MITSUBISHI RAYON CO., LTD. (JP) | 1986-03-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100098762-A1 | Thermosensitive Pluronic Derivative Hydrogels With High Biodegradability And Biocompatibility For Tissue Regeneration And Preparation Method Thereof | MKI67, CD44, FIBP | POLB 3377/4885APEX1 2100/4885HTT 4356/4885 |
| US-20030230487-A1 | Electrophoretic composition, image display medium using same and image display device | NEFM, ERGIC1, VCL | POLB 3273/4885APEX1 3516/4885HTT 1956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.