Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 1/20 | 0.50 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.50 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.50 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.50 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26978240 | 0.88 | KDM4E (0.50) | MAPTTHRBKDM4EPTPN2PTPN1 | |
| SCHEMBL3718737 | 0.88 | ALDH1A1 (0.52) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL5729820 | 0.84 | MAPT (0.38) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL5429190 | 0.84 | ALDH1A1 (0.46) | MAPTKDM4EALDH1A1HTTNPC1 | |
| SCHEMBL13160410 | 0.83 | KDM4E (0.52) | MAPTTHRBKDM4EALDH1A1PTPN2 | |
| SCHEMBL27712946 | 0.82 | ALDH1A1 (0.40) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL5449859 | 0.82 | EED (0.49) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL2775462 | 0.81 | ALDH1A1 (0.51) | MAPTKDM4EALDH1A1NPC1MAPK1 | |
| SCHEMBL25483959 | 0.79 | STS (0.50) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL3662027 | 0.78 | ADORA1 (0.46) | MAPTKDM4EALDH1A1GPR119TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070099929-A1 | Substituted thiophenes | AICURIS GMBH & CO. KG (DE) | 2007-05-03 | — | — | US | disclosed |
| US-20070099929-A1 | Substituted thiophenes | AICURIS GMBH & CO. KG (DE) | 2007-05-03 | — | — | US | disclosed |
| US-20070099929-A1 | Substituted thiophenes | AICURIS GMBH & CO. KG (DE) | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099929-A1 | Substituted thiophenes | TPMT, HAVCR2, MTAP | EED 2833/4885RBBP4 1880/4885SUZ12 1260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.