Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | REV1 | Q9UBZ9 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | CFTR | P13569 | 2/20 | 0.33 |
| ▸ | EED | O75530 | 1/20 | 0.33 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.33 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5729820 | 0.90 | MAPT (0.38) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL5441982 | 0.82 | EED (0.50) | ALDH1A1MAPTKDM4ENPC1RAB9A | |
| SCHEMBL27693406 | 0.82 | REV1 (0.35) | KDM4ENPC1RAB9AREV1CHRM2 | |
| SCHEMBL2775462 | 0.82 | ALDH1A1 (0.51) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL5429190 | 0.80 | ALDH1A1 (0.46) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL21247632 | 0.78 | ALDH1A1 (0.48) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL27811329 | 0.74 | RBP4 (0.48) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL27634998 | 0.73 | TSHR (0.45) | ALDH1A1HPGDMEN1KMT2ACHRM2 | |
| SCHEMBL28123114 | 0.73 | QDPR (0.34) | ALDH1A1MAPTHPGDKDM4ENPC1 | |
| SCHEMBL5732124 | 0.73 | EED (0.35) | MAPTKDM4ENPC1RAB9AREV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101094845-A | Substituted thiophenes | AICURIS GMBH & CO KG (DE) | 2007-12-26 | — | — | CN | disclosed |