Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 3/20 | 0.36 |
| ▸ | HTR7 | P34969 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | BRAF | P15056 | 6/20 | 0.34 |
| ▸ | MAPK3 | P27361 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.34 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5444207 | 1.00 | HTT (0.45) | HTTHSD17B10LMNAHPGDL3MBTL1 | |
| SCHEMBL353940 | 0.77 | HTT (0.49) | HTTHSD17B10LMNAHPGDL3MBTL1 | |
| SCHEMBL353939 | 0.77 | HTT (0.49) | HTTHSD17B10LMNAHPGDL3MBTL1 | |
| SCHEMBL5444174 | 0.73 | PBRM1 (0.53) | HSD17B10HPGDHTR1AHTR7HTR2A | |
| SCHEMBL18762883 | 0.73 | HTT (0.49) | HTTHSD17B10LMNAHPGDL3MBTL1 | |
| SCHEMBL25295761 | 0.73 | HTT (0.49) | HTTHSD17B10LMNAHPGDL3MBTL1 | |
| SCHEMBL8312278 | 0.73 | HTT (0.73) | HTTHSD17B10LMNAHPGDL3MBTL1 | |
| SCHEMBL9669635 | 0.73 | HTT (0.49) | HTTHSD17B10LMNAHPGDL3MBTL1 | |
| SCHEMBL595554 | 0.73 | HTT (0.49) | HTTHSD17B10LMNAHPGDL3MBTL1 | |
| SCHEMBL8312277 | 0.73 | HTT (0.73) | HTTHSD17B10LMNAHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070021450-A1 | Indanylamino uracils and their use as antioxidants and neuroprotectants | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2007-01-25 | — | — | US | disclosed |
| US-20070021450-A1 | Indanylamino uracils and their use as antioxidants and neuroprotectants | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2007-01-25 | — | — | US | disclosed |
| US-20070021450-A1 | Indanylamino uracils and their use as antioxidants and neuroprotectants | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2007-01-25 | — | — | US | disclosed |
| WO-2006020070-A2 | INDANYLAMINO URACILS AND THEIR USE AS ANTIOXIDANTS AND NEUROPROTECTANTS | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2006-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021450-A1 | Indanylamino uracils and their use as antioxidants and neuroprotectants | OGG1, CBR3, C1R | HTT 739/4885HSD17B10 1660/4885LMNA 1220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.