Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7237468 | 0.89 | MAOA (0.48) | PBRM1ALDH1A1HSD17B10HPGDCYP3A4 | |
| SCHEMBL6776955 | 0.85 | CASP1 (0.53) | PBRM1ALDH1A1HSD17B10CASP1CASP7 | |
| SCHEMBL17080971 | 0.81 | TERT (0.42) | PBRM1ALDH1A1HSD17B10HPGDACHE | |
| SCHEMBL14596263 | 0.77 | HTR7 (0.38) | ALDH1A1HSD17B10HPGDCYP3A4HIF1A | |
| SCHEMBL4741050 | 0.76 | RXRA (0.47) | PBRM1ALDH1A1ACHETSHRMAOA | |
| SCHEMBL3994800 | 0.75 | HSD17B1 (0.63) | HSD17B10CASP1CASP7CYP26A1MIF | |
| SCHEMBL7233780 | 0.75 | ACHE (0.48) | ALDH1A1ACHEPTGS2APPKDM4E | |
| SCHEMBL7233776 | 0.75 | ACHE (0.48) | ALDH1A1ACHEPTGS2APPKDM4E | |
| SCHEMBL10483513 | 0.74 | ALDH1A1 (0.47) | ALDH1A1HSD17B10HPGDCYP3A4HIF1A | |
| SCHEMBL11872289 | 0.74 | MAOB (0.56) | ALDH1A1HSD17B10HPGDCASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9994661-B2 | Curable composition, cured product, optical component, lens, and compound | FUJIFILM CORPORATION (JP) | 2018-06-12 | — | — | US | disclosed |
| US-20170342181-A1 | CURABLE COMPOSITION, CURED PRODUCT, OPTICAL COMPONENT, LENS, AND COMPOUND | FUJIFILM CORPORATION (JP) | 2017-11-30 | — | — | US | disclosed |
| US-20070021450-A1 | Indanylamino uracils and their use as antioxidants and neuroprotectants | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2007-01-25 | — | — | US | disclosed |
| US-20070021450-A1 | Indanylamino uracils and their use as antioxidants and neuroprotectants | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2007-01-25 | — | — | US | disclosed |
| US-20070021450-A1 | Indanylamino uracils and their use as antioxidants and neuroprotectants | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2007-01-25 | — | — | US | disclosed |
| WO-2006020070-A2 | INDANYLAMINO URACILS AND THEIR USE AS ANTIOXIDANTS AND NEUROPROTECTANTS | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2006-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170342181-A1 | CURABLE COMPOSITION, CURED PRODUCT, OPTICAL COMPONENT, LENS, AND COMPOUND | CRYAA, UACA, CRYAB | PBRM1 1680/4885ALDH1A1 424/4885BRD4 3002/4885 |
| US-20070021450-A1 | Indanylamino uracils and their use as antioxidants and neuroprotectants | OGG1, CBR3, C1R | PBRM1 4260/4885ALDH1A1 1798/4885BRD4 3129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.