Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | CTSG | P08311 | 1/20 | 0.36 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5441065 | 0.77 | ALDH1A1 (0.48) | PRSS1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL5435637 | 0.75 | CA1 (0.42) | KDM4EALDH1A1GAAGRIA1GRIA2 | |
| SCHEMBL4936612 | 0.71 | MEN1 (0.44) | MEN1KMT2AKDM4EPOLBALDH1A1 | |
| SCHEMBL14778954 | 0.71 | MEN1 (0.44) | MEN1KMT2AKDM4EPOLBALDH1A1 | |
| SCHEMBL28078215 | 0.70 | MEN1 (0.43) | MEN1KMT2AKDM4EPOLBALDH1A1 | |
| SCHEMBL5633234 | 0.69 | TSHR (0.42) | CASP6SLC22A12CYP2A6MAPT | |
| SCHEMBL1196441 | 0.69 | MEN1 (0.62) | TBXA2RMEN1KMT2AKDM4EPOLB | |
| SCHEMBL2892307 | 0.69 | SLC22A12 (0.63) | MEN1KMT2AALDH1A1SLC22A12CA1 | |
| SCHEMBL9913658 | 0.69 | ALDH1A1 (0.40) | PRSS1MEN1KMT2AALDH1A1CYP2A6 | |
| SCHEMBL10360517 | 0.68 | KMT2A (0.42) | MEN1KMT2AKDM4EPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070100149-A1 | PROCESS FOR PREPARING LETROZOLE | DR. REDDY'S LABORATORIES, INC. | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070100149-A1 | PROCESS FOR PREPARING LETROZOLE | CYP19A1, CYP2C19, CYP17A1 | CASP6 650/4885PRSS1 291/4885CTSG 395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.