Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | ESR1 | P03372 | 2/20 | 0.62 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2233407 | 0.80 | TDP1 (0.54) | MEN1KMT2ATDP1L3MBTL1GAA | |
| SCHEMBL1196442 | 0.78 | MEN1 (0.60) | MEN1KMT2ATDP1L3MBTL1GAA | |
| SCHEMBL1195227 | 0.76 | ALPL (0.48) | ALPLALDH1A1HPGDCA1CA2 | |
| SCHEMBL11856777 | 0.73 | MEN1 (0.58) | MEN1KMT2AESR1ESR2ATM | |
| SCHEMBL29776988 | 0.72 | POLB (0.62) | MEN1KMT2AESR1ESR2ATM | |
| SCHEMBL6912873 | 0.72 | POLB (0.62) | MEN1KMT2AESR1ESR2ATM | |
| SCHEMBL1196445 | 0.71 | KMT2A (0.55) | KMT2ATDP1L3MBTL1GAAMAPK1 | |
| SCHEMBL1195899 | 0.71 | HSD11B1 (0.45) | CA1CA2CA9 | |
| SCHEMBL9491080 | 0.70 | POLB (0.60) | MEN1KMT2AESR1ESR2ATM | |
| SCHEMBL11026640 | 0.70 | MEN1 (0.71) | MEN1KMT2AESR1ESR2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110040115-A1 | INTERMEDIATES AND PROCESS FOR THE PREPARATION OF AROMATIC DERIVATIVES OF 1-ADAMANTANE | FINORGA SAS (FR) | 2011-02-17 | — | — | US | disclosed |
| EP-1986985-B1 | INTERMEDIATES AND PROCESS FOR THE PREPARATION OF AROMATIC DERIVATIVES OF 1-ADAMANTANE | FINORGA SAS (FR) | 2010-09-01 | — | — | EP | disclosed |
| EP-1986985-A1 | INTERMEDIATES AND PROCESS FOR THE PREPARATION OF AROMATIC DERIVATIVES OF 1-ADAMANTANE | FINORGA SAS (FR) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007063523-A1 | INTERMEDIATES AND PROCESS FOR THE PREPARATION OF AROMATIC DERIVATIVES OF 1-ADAMANTANE | FINORGA SAS (FR) | 2007-06-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110040115-A1 | INTERMEDIATES AND PROCESS FOR THE PREPARATION OF AROMATIC DERIVATIVES OF 1-ADAMANTANE | DHPS, APOBEC3A, DDC | MEN1 4490/4885KMT2A 4560/4885ESR1 4779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.