Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | NT5E | P21589 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | TOP2A | P11388 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | PTGES | O14684 | 1/20 | 0.52 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.45 |
| ▸ | F3 | P13726 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | GLI1 | P08151 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14374306 | 1.00 | LMNA (0.56) | LMNANT5EUSP2HIF1ATOP2A | |
| SCHEMBL14397737 | 1.00 | LMNA (0.56) | LMNANT5EUSP2HIF1ATOP2A | |
| SCHEMBL5447022 | 0.90 | LMNA (0.57) | LMNANT5EUSP2HIF1ATOP2A | |
| SCHEMBL14374330 | 0.90 | LMNA (0.57) | LMNANT5EUSP2HIF1ATOP2A | |
| SCHEMBL6715660 | 0.89 | LMNA (0.58) | LMNANT5EUSP2HIF1ATOP2A | |
| SCHEMBL7747717 | 0.89 | LMNA (0.58) | LMNANT5EUSP2HIF1ATOP2A | |
| SCHEMBL14399283 | 0.87 | SLC10A1 (0.40) | LMNANT5EUSP2HIF1ATOP2A | |
| SCHEMBL5439801 | 0.86 | LMNA (0.55) | LMNANT5EUSP2HIF1ATOP2A | |
| SCHEMBL14374327 | 0.86 | LMNA (0.55) | LMNANT5EUSP2HIF1ATOP2A | |
| SCHEMBL14399285 | 0.86 | LMNA (0.54) | LMNANT5EUSP2HIF1ATOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070232577-A1 | Synthetic pentacyclic triterpenoids and derivatives of betulinic acid and betulin | ADVANCED LIFE SCIENCES, INC. (US) | 2007-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232577-A1 | Synthetic pentacyclic triterpenoids and derivatives of betulinic acid and betulin | BET1, PGGT1B, BRCA1 | LMNA 4313/4885NT5E 3553/4885USP2 4593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.