Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 10/20 | 0.49 |
| ▸ | DRD2 | P14416 | 5/20 | 0.49 |
| ▸ | DRD4 | P21917 | 5/20 | 0.49 |
| ▸ | DRD3 | P35462 | 4/20 | 0.49 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | HTR3B | O95264 | 2/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.46 |
| ▸ | DRD1 | P21728 | 2/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3688075 | 0.80 | DRD2 (0.51) | CHRM1DRD2DRD4DRD3HTR3E | |
| Hydrochloric Acid SCHEMBL5472406 | 0.77 | HRH4 (0.48) | CHRM1DRD2DRD4DRD3MEN1 | |
| SCHEMBL9406688 | 0.77 | DRD2 (0.48) | CHRM1DRD2DRD4DRD3HTR3E | |
| SCHEMBL4447696 | 0.75 | CHRM1 (0.52) | CHRM1DRD2DRD4DRD3HTR3E | |
| SCHEMBL7404821 | 0.75 | CHRM1 (0.50) | CHRM1DRD2DRD4DRD3HTR3E | |
| Hydrochloric Acid SCHEMBL5740086 | 0.74 | CHRM1 (0.49) | CHRM1DRD2DRD4DRD3HTR3E | |
| SCHEMBL30416496 | 0.74 | DRD2 (0.56) | CHRM1DRD2DRD4DRD3HTR3E | |
| SCHEMBL3277971 | 0.74 | DRD2 (0.56) | CHRM1DRD2DRD4DRD3HTR3E | |
| SCHEMBL3858770 | 0.74 | CHRM1 (0.47) | CHRM1DRD2DRD4DRD3HTR3E | |
| Hydrochloric Acid SCHEMBL5445211 | 0.73 | DRD2 (0.55) | CHRM1DRD2DRD4DRD3HTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197957-A1 | Implantable sensors, implantable pumps and anti-scarring drug combinations | HUNTER WILLIAM L | 2007-08-23 | — | — | US | disclosed |