Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1F | O60840 | 5/20 | 0.58 |
| ▸ | CACNA1D | Q01668 | 5/20 | 0.58 |
| ▸ | CACNA1S | Q13698 | 5/20 | 0.58 |
| ▸ | CACNA1C | Q13936 | 5/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4106662 | 0.91 | CACNA1F (0.48) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL5443406 | 0.90 | ALDH1A1 (0.49) | CACNA1FCACNA1DCACNA1SCACNA1CALDH1A1 | |
| SCHEMBL5447133 | 0.89 | CACNA1F (0.60) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL5454285 | 0.86 | ALDH1A1 (0.52) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL5442459 | 0.84 | CACNA1F (0.48) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL10891614 | 0.83 | ADORA3 (0.64) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL4112688 | 0.83 | ALDH1A1 (0.43) | CACNA1FCACNA1DCACNA1SCACNA1CALDH1A1 | |
| SCHEMBL5452965 | 0.83 | ALDH1A1 (0.51) | CACNA1FCACNA1DCACNA1SCACNA1CALDH1A1 | |
| SCHEMBL5463708 | 0.82 | CACNA1F (0.41) | CACNA1FCACNA1DCACNA1SCACNA1CALDH1A1 | |
| SCHEMBL15026364 | 0.81 | ALDH1A1 (0.62) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070037807-A1 | Pyridine compounds as inhibitors of dipeptidyl peptidase IV | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037807-A1 | Pyridine compounds as inhibitors of dipeptidyl peptidase IV | DPP4, DPP3, PEPD | CACNA1F 2405/4885CACNA1D 2524/4885CACNA1S 1988/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.