SCHEMBL544564

SCHEMBL544564

O=C1CN(CC2CO2)C(=O)N1

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.48
HBB P68871 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
DHFR P00374 1/20 0.36
CRBN Q96SW2 1/20 0.35
TOP2A P11388 2/20 0.33
TOP2B Q02880 2/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
PTGS1 P23219 2/20 0.32
LMNA P02545 1/20 0.32
EPHX2 P34913 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11601033 0.81 TP53 (0.45) TP53HBBSMN1; SMN2DHFRCRBN
SCHEMBL28859151 0.78 CRBN (0.35) TP53HBBSMN1; SMN2CRBNALDH1A1
SCHEMBL17160675 0.77 TSHR (0.38) TP53HBBSMN1; SMN2CRBNALDH1A1
SCHEMBL12004346 0.75 CRBN (0.38) SMN1; SMN2CRBNTOP2ATOP2BALDH1A1
SCHEMBL7338893 0.72 PIK3CA (0.39) CRBNMAPT
SCHEMBL8999579 0.71 CRBN (0.46) CRBNTOP2ATOP2BALDH1A1MAPT
SCHEMBL11598636 0.70 TP53 (0.56) TP53HBBSMN1; SMN2DHFRALDH1A1
SCHEMBL3471790 0.70 TP53 (0.56) TP53HBBSMN1; SMN2DHFRALDH1A1
SCHEMBL11600178 0.69 HBB (0.50) TP53HBBSMN1; SMN2DHFRALDH1A1
SCHEMBL25808010 0.68 CRBN (0.44) CRBNTOP2ATOP2BALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 417 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118326556-A Medical composite fiber material and preparation method thereof 扬州卓和医用材料有限公司 2024-07-12 CN claimed
CN-118271022-A Impact-resistant and wear-resistant agent for concrete and preparation method thereof 新疆恒泰林茂材料科技有限公司 2024-07-02 CN claimed
CN-118241128-A Copper-aluminum alloy finned tube and production process thereof 扬州昊然机械配件有限公司 2024-06-25 CN claimed
CN-116836388-B Positive photosensitive resin, resin composition, preparation method and application thereof 明士(北京)新材料开发有限公司 2023-12-15 CN claimed
CN-117106290-A High-transparency durable PET material and preparation method thereof 江苏宸之光新材料科技有限公司 2023-11-24 CN claimed
CN-116836388-A Positive photosensitive resin, resin composition, preparation method and application thereof 明士(北京)新材料开发有限公司 2023-10-03 CN claimed
US-11453143-B2 Treated porous material DOW GLOBAL TECHNOLOGIES LLC (US) 2022-09-27 US claimed
CN-113004845-B Anionic photocuring mercaptan-epoxy adhesive 江南大学 2022-05-17 CN claimed
CN-114446562-A Die-pressing inductor made of aqueous epoxy resin and manufacturing process thereof 上海太朔材料技术有限公司 2022-05-06 CN claimed
CN-110804335-B Flame-retardant epoxy putty and preparation method and application thereof 株洲时代新材料科技股份有限公司 2021-11-16 CN claimed
WO-2006052727-A1 AMPHIPHILIC BLOCK COPOLYMER-TOUGHENED EPOXY RESINS AND ELECTRICAL LAMINATES MADE THEREFROM DOW GLOBAL TECHNOLOGIES INC. (US) 2006-05-18 WO claimed
WO-2006052730-A1 AMPHIPHILIC BLOCK COPOLYMER-TOUGHENED EPOXY RESINS AND POWDER COATINGS MADE THEREFROM DOW GLOBAL TECHNOLOGIES INC. (US) 2006-05-18 WO claimed
WO-2006052726-A1 AMPHIPHILIC BLOCK COPOLYMER-MODIFIED EPOXY RESINS AND ADHESIVES MADE THEREFROM DOW GLOBAL TECHNOLOGIES, INC. (US) 2006-05-18 WO claimed
WO-2006052725-A1 AMPHIPHILIC BLOCK COPOLYMER-TOUGHENED EPOXY RESINS AND AMBIENT CURE HIGH-SOLIDS COATINGS MADE THEREFROM DOW GLOBAL TECHNOLOGIES INC. (US) 2006-05-18 WO claimed
WO-2006052729-A1 AMPHIPHILIC BLOCK COPOLYMER-TOUGHENED EPOXY RESINS DOW GLOBAL TECHNOLOGIES INC. (US) 2006-05-18 WO claimed
WO-2005097893-A1 AMPHIPHILIC BLOCK COPOLYMER-TOUGHENED THERMOSET RESINS DOW GLOBAL TECHNOLOGIES INC. (US) 2005-10-20 WO claimed
EP-0187121-A1 Heat-curable epoxy resin compositions CIBA-GEIGY AG (CH) 1986-07-09 EP claimed
US-4535121-A BLEND OF POLYURETHANE WITH AROMATIC DIISOCYANATE AND EPOXIDE HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1985-08-13 US claimed
US-4145247-A POLYEPOXIDES CIBA-GEIGY CORPORATION (US) 1979-03-20 US claimed
US-4117029-A VINYL CHLORIDE POLYE NITTO KASEI CO. LTD. (JP) 1978-09-26 US claimed