Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | QPCT | Q16769 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL10657586 | 0.92 | ALDH1A1 (0.41) | KMT2ACYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL2108064 | 0.86 | SPHK1 (0.41) | KMT2ASMN1; SMN2LMNAKDM4E | |
| SCHEMBL11724194 | 0.84 | SPHK1 (0.44) | KMT2AKDM4E | |
| SCHEMBL10546875 | 0.84 | SPHK1 (0.44) | KMT2AKDM4E | |
| SCHEMBL11729772 | 0.84 | SPHK1 (0.44) | KMT2AKDM4E | |
| SCHEMBL11725057 | 0.84 | SPHK1 (0.44) | KMT2AKDM4E | |
| SCHEMBL11729895 | 0.84 | SPHK1 (0.44) | KMT2AKDM4E | |
| SCHEMBL11727348 | 0.84 | SPHK1 (0.44) | KMT2AKDM4E | |
| SCHEMBL11727025 | 0.84 | SPHK1 (0.44) | KMT2AKDM4E | |
| SCHEMBL11726657 | 0.84 | SPHK1 (0.44) | KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |
| US-3960949-A | DIABETES | SCHERING AKTIENGESELLSCHAFT (DT) | 1976-06-01 | — | — | US | disclosed |