Diphenylmethane

Diphenylmethane

SCHEMBL544612

[KH].c1ccc(Cc2ccccc2)cc1

nearest known ligand 0.92

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.92
LTA4H P09960 1/20 0.55
IDH1 O75874 1/20 0.52
TSHR P16473 3/20 0.50
ALDH1A1 P00352 2/20 0.50
IDO1 P14902 1/20 0.50
TP53 P04637 1/20 0.50
PLA2G10 O15496 1/20 0.50
PLA2G2A P14555 1/20 0.50
LOXL2 Q9Y4K0 1/20 0.50
LMNA P02545 1/20 0.50
BCL2 P10415 1/20 0.50
BCL2L1 Q07817 1/20 0.50
TRPA1 O75762 1/20 0.50
SLC22A2 O15244 1/20 0.48
KDM4E B2RXH2 1/20 0.48
CYP3A4 P08684 1/20 0.48
MAPT P10636 1/20 0.48
MAOB P27338 1/20 0.47
HPGD P15428 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylmethane SCHEMBL28172316 0.96 CALM1 (1.00) CALM1LTA4HIDH1TSHRALDH1A1
Diphenylmethane SCHEMBL1303 0.96 CALM1 (1.00) CALM1LTA4HIDH1TSHRALDH1A1
Diphenylmethane SCHEMBL4361124 0.96 CALM1 (1.00) CALM1LTA4HIDH1TSHRALDH1A1
Diphenylmethane SCHEMBL14763944 0.96 CALM1 (1.00) CALM1LTA4HIDH1TSHRALDH1A1
Diphenylmethane SCHEMBL3792579 0.96 CALM1 (1.00) CALM1LTA4HIDH1TSHRALDH1A1
Diphenylmethane SCHEMBL25402252 0.92 CALM1 (0.92) CALM1LTA4HIDH1TSHRALDH1A1
Diphenylmethane SCHEMBL2386917 0.92 CALM1 (0.92) CALM1LTA4HIDH1TSHRALDH1A1
Diphenylmethane SCHEMBL9958926 0.92 CALM1 (0.92) CALM1LTA4HIDH1TSHRALDH1A1
Diphenylmethane SCHEMBL22462139 0.92 CALM1 (0.92) CALM1LTA4HIDH1TSHRALDH1A1
Diphenylmethane SCHEMBL3750008 0.92 CALM1 (0.92) CALM1LTA4HIDH1TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8110641-B2 Anionic polymerization method for styrene derivative containing pyridine as functional group GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2012-02-07 US claimed
US-8110642-B2 Synthesis of vinylphenylpyridine and living anionic polymerization GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2012-02-07 US claimed
EP-1757631-B1 Amphiphilic triblock copolymers comprising poly(2-vinyl pyridine) block and poly(alkyl isocyanate) block, and the preparation method thereof KWANGJU INST SCI & TECH (KR) 2010-02-24 EP claimed
US-20090203861-A1 ANIONIC POLYMERIZATION METHOD FOR STYRENE DERIVATIVE CONTAINING PYRIDINE AS FUNCTIONAL GROUP GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2009-08-13 US claimed
US-20090105416-A1 Synthesis of Vinylphenylpyridine and Living Anionic Polymerization GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2009-04-23 US claimed
US-7425593-B2 Amphiphilic triblock copolymers comprising poly(2-vinylpyridine) block and poly(alkyl isocyanate) block, and the preparation method thereof GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2008-09-16 US claimed
WO-2007129810-A1 SYNTHESIS OF VINYLPHENYLPYRIDINE AND LIVING ANIONIC POLYMERIZATION GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2007-11-15 WO claimed
US-20070060705-A1 Amphiphilic triblock copolymers comprising poly(2-vinylpyridine) block and poly(alkyl isocyanate) block, and the preparation method thereof GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY 2007-03-15 US claimed
EP-1757631-A1 Amphiphilic triblock copolymers comprising poly(2-vinyl pyridine) block and poly(alkyl isocyanate) block, and the preparation method thereof Gwangju Institute of Science and Technology (GIST) (KR) 2007-02-28 EP claimed
US-20050215755-A1 Poly(2-vinylpyridine)-b-poly(n-hexylisocyanate) amphiphilic coil-rod block copolymer and polymerization method thereof GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2005-09-29 US claimed
CN-110128613-A A kind of aqueous polyurethane for high permeability steam leather 温州大学 2019-08-16 CN disclosed
CN-108250415-A A kind of poly- (gamma-butyrolacton)-b- polylactic-acid block copolymers and preparation method thereof 青岛科技大学 2018-07-06 CN disclosed
CN-102757564-B Preparation method and application of tree-like polyester-polyglycidol block polymer UNIV TIANJIN TECHNOLOGY 2013-12-11 CN disclosed
CN-102757564-A Preparation method and application of tree-like polyester-polyglycidol block polymer UNIV TIANJIN TECHNOLOGY 2012-10-31 CN disclosed
US-8110642-B2 Synthesis of vinylphenylpyridine and living anionic polymerization GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2012-02-07 US disclosed
US-20070060705-A1 Amphiphilic triblock copolymers comprising poly(2-vinylpyridine) block and poly(alkyl isocyanate) block, and the preparation method thereof GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY 2007-03-15 US disclosed
EP-1757631-A1 Amphiphilic triblock copolymers comprising poly(2-vinyl pyridine) block and poly(alkyl isocyanate) block, and the preparation method thereof Gwangju Institute of Science and Technology (GIST) (KR) 2007-02-28 EP disclosed
JP-2005281671-A AMPHIPHATIC COIL-ROD TYPE 2-VINYLPYRIDINE/N-HEXYLISOCYANATE BLOCK COPOLYMER AND METHOD FOR PRODUCING THE SAME KWANGJU INST OF SCIENCE & TECHNOL 2005-10-13 JP disclosed
US-20050215755-A1 Poly(2-vinylpyridine)-b-poly(n-hexylisocyanate) amphiphilic coil-rod block copolymer and polymerization method thereof GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2005-09-29 US disclosed
US-20050215755-A1 Poly(2-vinylpyridine)-b-poly(n-hexylisocyanate) amphiphilic coil-rod block copolymer and polymerization method thereof GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2005-09-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090105416-A1 Synthesis of Vinylphenylpyridine and Living Anionic Polymerization PBRM1, MVD, PCBP1 CALM1 921/4885LTA4H 1451/4885IDH1 62/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.