Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.31 |
| ▸ | GGT1 | P19440 | 1/20 | 0.31 |
| ▸ | ARG1 | P05089 | 1/20 | 0.31 |
| ▸ | ARG2 | P78540 | 1/20 | 0.31 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.30 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.30 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL168535 | 1.00 | MEN1 (0.35) | MEN1CYP1A2KMT2AALDH1A1THRB | |
| Acetic Acid SCHEMBL1970151 | 0.98 | MEN1 (0.34) | MEN1CYP1A2KMT2AALDH1A1THRB | |
| Carbamic Acid SCHEMBL19211626 | 0.90 | MEN1 (0.35) | MEN1CYP1A2KMT2AALDH1A1THRB | |
| SCHEMBL321976 | 0.87 | — | — | |
| Acetic Acid SCHEMBL1970150 | 0.86 | CA1 (0.41) | FFAR3 | |
| Acetic Acid SCHEMBL5083116 | 0.86 | CA1 (0.36) | — | |
| Acetic Acid SCHEMBL5082566 | 0.86 | CA1 (0.36) | — | |
| SCHEMBL20678765 | 0.84 | — | — | |
| Trimethylammonium SCHEMBL27297434 | 0.79 | — | — | |
| Methyl Isobutyl Ketone SCHEMBL28129670 | 0.79 | ALDH1A1 (0.54) | ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070264218-A1 | Reducing Composition for Permanent Wave or Straight Permanent | KAO CORPORATION (JP) | 2007-11-15 | — | — | US | disclosed |
| US-6383269-B1 | AQUEOUS ELECTROLYTES FOR IMMERSION PLATING | SHIPLEY COMPANY, L.L.C. | 2002-05-07 | — | — | US | disclosed |
| EP-1026285-A2 | Electroless gold plating solution and process | Shipley Company LLC (US) | 2000-08-09 | — | — | EP | disclosed |
| EP-0281696-B1 | A PROCESS FOR THE PHOTOCATALYTIC DECOMPOSITION OF WATER INTO HYDROGEN AND OXYGEN | Council of Scientific and Industrial Research (IN) | 1992-01-02 | — | — | EP | disclosed |
| US-4889604-A | Process for the photocatalytic decomposition of water into hydrogen and oxygen | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 1989-12-26 | — | — | US | disclosed |
| EP-0281696-A1 | A process for the photocatalytic decomposition of water into hydrogen and oxygen | Council of Scientific and Industrial Research (IN) | 1988-09-14 | — | — | EP | disclosed |
| US-4578156-A | Electrolytes for electrochemically treating metal plates | AMERICAN HOECHST CORPORATION (US) | 1986-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070264218-A1 | Reducing Composition for Permanent Wave or Straight Permanent | KRT18, TST, MGMT | MEN1 4611/4885CYP1A2 3054/4885KMT2A 1369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.