Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | HTT | P42858 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.63 |
| ▸ | MITF | O75030 | 1/20 | 0.63 |
| ▸ | XBP1 | P17861 | 1/20 | 0.63 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.63 |
| ▸ | ABL1 | P00519 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | KDR | P35968 | 2/20 | 0.54 |
| ▸ | BRAF | P15056 | 1/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.54 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.51 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5438358 | 0.85 | ABL1 (0.56) | MAPTHTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5448580 | 0.84 | HTT (0.72) | MAPTHTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5439899 | 0.84 | MAPT (0.61) | MAPTHTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7429049 | 0.83 | NTRK1 (0.62) | MAPTHTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5447870 | 0.82 | KMT2A (0.70) | MAPTHTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5442589 | 0.82 | KMT2A (0.62) | MAPTHTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5439929 | 0.82 | MEN1 (0.59) | MAPTMEN1KMT2AABL1KDR | |
| SCHEMBL5444646 | 0.82 | BLM (0.74) | MAPTHTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3174300 | 0.82 | KDR (0.70) | MAPTHTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3467776 | 0.81 | MEN1 (0.56) | MAPTHTTMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070191353-A1 | Use of thiadiazoleurea derivatives | MERCK PATENT GMBH (DE) | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191353-A1 | Use of thiadiazoleurea derivatives | RAF1, ARAF, JAK1 | MAPT 3983/4885HTT 3825/4885MEN1 1756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.