Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.43 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.42 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1488258 | 0.82 | TSHR (0.50) | ALDH1A1LMNACYP2D6CYP2C19TAAR1 | |
| SCHEMBL8815051 | 0.80 | TSHR (0.46) | ALDH1A1LMNACYP2D6CYP2C19TAAR1 | |
| SCHEMBL239953 | 0.79 | ALDH1A1 (0.46) | ALDH1A1LMNACYP2D6CYP2C19TAAR1 | |
| SCHEMBL239954 | 0.79 | ALDH1A1 (0.46) | ALDH1A1LMNACYP2D6CYP2C19TAAR1 | |
| SCHEMBL4318714 | 0.79 | ALDH1A1 (0.46) | ALDH1A1LMNACYP2D6CYP2C19TAAR1 | |
| SCHEMBL10578482 | 0.77 | ALDH1A1 (0.59) | ALDH1A1LMNACYP2D6CYP2C19TAAR1 | |
| SCHEMBL15087214 | 0.77 | ALDH1A1 (0.52) | ALDH1A1LMNACYP2D6CYP2C19TAAR1 | |
| SCHEMBL10578491 | 0.77 | ALDH1A1 (0.59) | ALDH1A1LMNACYP2D6CYP2C19TAAR1 | |
| SCHEMBL13381419 | 0.77 | ALDH1A1 (0.52) | ALDH1A1LMNACYP2D6CYP2C19TAAR1 | |
| SCHEMBL17438007 | 0.76 | TSHR (0.42) | ALDH1A1LMNATSHRTP53EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8960247-B2 | Pneumatic tire | BRIDGESTONE CORPORATION (JP) | 2015-02-24 | — | — | US | disclosed |
| EP-2116396-B1 | PNEUMATIC TIRE | BRIDGESTONE CORP (JP) | 2014-04-23 | — | — | EP | disclosed |
| US-8110625-B2 | Rubber composition | BRIDGESTONE CORPORATION (JP) | 2012-02-07 | — | — | US | disclosed |
| EP-2223958-B1 | Rubber composition | BRIDGESTONE CORP (JP) | 2011-12-28 | — | — | EP | disclosed |
| US-20100298488-A1 | RUBBER COMPOSITION | BRIDGESTONE CORPORATION (JP) | 2010-11-25 | — | — | US | disclosed |
| US-7799856-B2 | Rubber composition | BRIDGESTONE CORPORATION (JP) | 2010-09-21 | — | — | US | disclosed |
| EP-2226354-A1 | Rubber composition | Bridgestone Corporation (JP) | 2010-09-08 | — | — | EP | disclosed |
| EP-2223958-A1 | Rubber composition | Bridgestone Corporation (JP) | 2010-09-01 | — | — | EP | disclosed |
| US-20100024937-A1 | PNEUMATIC TIRE | BRIDGESTONE CORPORATION (JP) | 2010-02-04 | — | — | US | disclosed |
| EP-2116396-A1 | PNEUMATIC TIRE | Bridgestone Corporation (JP) | 2009-11-11 | — | — | EP | disclosed |
| US-20040249032-A1 | Rubber composition | BRIDGESTONE CORPORATION (JP) | 2004-12-09 | — | — | US | disclosed |
| EP-1435375-A1 | RUBBER COMPOSITION | Bridgestone Corporation (JP) | 2004-07-07 | — | — | EP | disclosed |
| US-4374956-A | METAL ADHESIVES | MONSANTO COMPANY (US) | 1983-02-22 | — | — | US | disclosed |
| US-4350740-A | SUBSTITUTED MALEAMIC ACID MODIFIER; ADHESION TO METALS | MONSANTO COMPANY (US) | 1982-09-21 | — | — | US | disclosed |
| US-4320173-A | REINFORCEMENT AND ADHESIVES FOR VULCANIZED PRODUCTS | MONSANTO COMPANY (US) | 1982-03-16 | — | — | US | disclosed |
| US-4320173-A | REINFORCEMENT AND ADHESIVES FOR VULCANIZED PRODUCTS | MONSANTO COMPANY (US) | 1982-03-16 | — | — | US | disclosed |
| US-4320173-A | REINFORCEMENT AND ADHESIVES FOR VULCANIZED PRODUCTS | MONSANTO COMPANY (US) | 1982-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298488-A1 | RUBBER COMPOSITION | RAD50, RAD54L, VCL | ALDH1A1 3192/4885LMNA 377/4885CYP2D6 4333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.