Sugi Predict

Sugi Predict / Compounds / SCHEMBL239953

SCHEMBL239953

SCHEMBL239953

C=CCNC(=O)/C=C/C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 5/20 0.46
▸ LMNA P02545 2/20 0.46
▸ CYP2D6 P10635 1/20 0.46
▸ CYP2C19 P33261 1/20 0.46
▸ TSHR P16473 3/20 0.45
▸ SMN1; SMN2 Q16637 2/20 0.45
▸ MAPT P10636 1/20 0.45
▸ RAB9A P51151 2/20 0.44
▸ NPC1 O15118 1/20 0.44
▸ TAAR1 Q96RJ0 3/20 0.43
▸ KMT2A Q03164 1/20 0.42
▸ TP53 P04637 1/20 0.41
▸ EGLN1 Q9GZT9 1/20 0.41
▸ EGLN3 Q9H6Z9 1/20 0.41
▸ HPGD P15428 1/20 0.41
▸ GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL239954 1.00 ALDH1A1 (0.46) ALDH1A1LMNACYP2D6CYP2C19TSHR
SCHEMBL4318714 1.00 ALDH1A1 (0.46) ALDH1A1LMNACYP2D6CYP2C19TSHR
SCHEMBL6435439 0.91 SMN1; SMN2 (0.52) ALDH1A1LMNATSHRSMN1; SMN2MAPT
SCHEMBL6435438 0.91 SMN1; SMN2 (0.52) ALDH1A1LMNATSHRSMN1; SMN2MAPT
SCHEMBL4557966 0.80 ALDH1A1 (0.46) ALDH1A1TSHRSMN1; SMN2MAPTRAB9A
SCHEMBL6024492 0.80 SMN1; SMN2 (0.46) ALDH1A1LMNACYP2C19TSHRSMN1; SMN2
SCHEMBL5482541 0.80 ALDH1A1 (0.46) ALDH1A1TSHRSMN1; SMN2MAPTRAB9A
SCHEMBL9281803 0.80 ALDH1A1 (0.46) ALDH1A1TSHRSMN1; SMN2MAPTRAB9A
SCHEMBL544692 0.79 ALDH1A1 (0.47) ALDH1A1LMNACYP2D6CYP2C19TSHR
Maleic Acid SCHEMBL16228194 0.78 TSHR (0.47) ALDH1A1LMNATSHRSMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 154 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11912831-B2 Hydroxyethylpyrrolidone ethacrylate/glycidyl ethacrylate copolymers ISP INVESTMENTS LLC (US) 2024-02-27 — — US disclosed
US-20230142648-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2023-05-11 — — US disclosed
EP-4114825-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2023-01-11 — — EP disclosed
US-20220121113-A1 OXIME ESTER PHOTOINITIATORS HAVING A SPECIAL AROYL CHROMOPHORE BASF SE (DE) 2022-04-21 — — US disclosed
US-11209733-B2 Oxime ester photoinitiators BASF SE 2021-12-28 — — US disclosed
US-11209734-B2 Oxime ester photoinitiators BASF SE 2021-12-28 — — US disclosed
EP-3044208-B1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2021-12-22 — — EP disclosed
US-11204554-B2 Oxime ester photoinitiators BASF SE 2021-12-21 — — US disclosed
EP-3914965-A1 OXIME ESTER PHOTOINITIATORS HAVING A SPECIAL AROYL CHROMOPHORE BASF SE (DE) 2021-12-01 — — EP disclosed
WO-2021175855-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2021-09-10 — — WO disclosed
EP-1784449-A1 COMPOSITIONS CONTAINING ANTHRAQUINONE DYES Huntsman Advanced Materials (Switzerland) GmbH (CH) 2007-05-16 — — EP disclosed
EP-1778636-A1 OXIME ESTER PHOTOINITIATORS Ciba SC Holding AG (CH) 2007-05-02 — — EP disclosed
US-20060241259-A1 Oxime ester photoinitiators with heteroaromatic groups CIBA CORPORATION 2006-10-26 — — US disclosed
WO-2006037728-A1 USE OF PYRIMIDO[5,4-G]PTERIDINES AS SHADING COMPONENT IN COLOR FILTER COLORANT COMPOSITIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-04-13 — — WO disclosed
WO-2006024617-A1 COMPOSITIONS CONTAINING ANTHRAQUINONE DYES HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (CH) 2006-03-09 — — WO disclosed
WO-2006024618-A1 CYANOPYRIDINE-BASED AZO DYES HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (CH) 2006-03-09 — — WO disclosed
WO-2006024619-A1 COMPOSITIONS CONTAINING PHTHALOCYANINE DYES HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (CH) 2006-03-09 — — WO disclosed
WO-2006018405-A1 OXIME ESTER PHOTOINITIATORS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-02-23 — — WO disclosed
EP-1567518-A2 OXIME ESTER PHOTOINITIATORS WITH HETEROAROMATIC GROUPS Ciba SC Holding AG (CH) 2005-08-31 — — EP disclosed
WO-2004050653-A2 OXIME ESTER PHOTOINITIATORS WITH HETEROAROMATIC GROUPS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-06-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11209734-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 ALDH1A1 823/4885LMNA 2575/4885CYP2D6 89/4885
US-11204554-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 ALDH1A1 779/4885LMNA 2745/4885CYP2D6 85/4885
US-11912831-B2 Hydroxyethylpyrrolidone ethacrylate/glycidyl ethacrylate copolymers MMAB, PCNA, HMBS ALDH1A1 263/4885LMNA 2499/4885CYP2D6 2555/4885
US-11209733-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 ALDH1A1 823/4885LMNA 2575/4885CYP2D6 89/4885
US-20230142648-A1 OXIME ESTER PHOTOINITIATORS OCIAD1, OCIAD2, OXER1 ALDH1A1 964/4885LMNA 3831/4885CYP2D6 350/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.