Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14940191 | 0.79 | RAPGEF4 (0.54) | RAPGEF4CRHR1 | |
| SCHEMBL14940545 | 0.79 | RAPGEF4 (0.54) | RAPGEF4CRHR1 | |
| SCHEMBL5443606 | 0.79 | RAPGEF4 (0.48) | RAPGEF4CRHR1 | |
| SCHEMBL1181478 | 0.78 | RAPGEF4 (0.52) | RAPGEF4CRHR1 | |
| SCHEMBL1182707 | 0.76 | RAPGEF4 (0.45) | RAPGEF4CRHR1 | |
| SCHEMBL14347189 | 0.75 | RAPGEF4 (0.58) | RAPGEF4CRHR1 | |
| SCHEMBL1672474 | 0.72 | POLB (0.50) | — | |
| SCHEMBL9123851 | 0.72 | KMT2A (0.43) | — | |
| SCHEMBL9878202 | 0.72 | ALDH1A1 (0.54) | — | |
| SCHEMBL14940406 | 0.72 | RAPGEF4 (0.54) | RAPGEF4CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070270588-A1 | Pyrrolopyrimidine Derivatives | TAISHO PHARMACEUTICAL CO., LTD. | 2007-11-22 | — | — | US | disclosed |
| US-20070270588-A1 | Pyrrolopyrimidine Derivatives | TAISHO PHARMACEUTICAL CO., LTD. | 2007-11-22 | — | — | US | disclosed |
| US-20070270588-A1 | Pyrrolopyrimidine Derivatives | TAISHO PHARMACEUTICAL CO., LTD. | 2007-11-22 | — | — | US | disclosed |
| EP-1725562-A1 | PYRROLOPYRIMIDINE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2006-11-29 | — | — | EP | disclosed |
| WO-2005085253-A1 | PYRROLOPYRIMIDINE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2005-09-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070270588-A1 | Pyrrolopyrimidine Derivatives | HRH2, ALPI, HRH1 | RAPGEF4 231/4885CRHR1 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.