Sugi Predict

Sugi Predict / Compounds / SCHEMBL5447378

SCHEMBL5447378

SCHEMBL5447378

Cc1cc(=O)n(-c2cc(S(=O)(=O)O)ccc2S(=O)(=O)O)[nH]1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 9/20 0.46
▸ ALDH1A1 P00352 8/20 0.46
▸ KDM4E B2RXH2 6/20 0.46
▸ SMN1; SMN2 Q16637 2/20 0.46
▸ KMT2A Q03164 7/20 0.44
▸ GAA P10253 3/20 0.44
▸ MEN1 O00255 3/20 0.44
▸ HTT P42858 2/20 0.44
▸ TDP1 Q9NUW8 3/20 0.41
▸ LMNA P02545 2/20 0.39
▸ RECQL P46063 1/20 0.39
▸ KDM5A P29375 1/20 0.37
▸ KDM2B Q8NHM5 1/20 0.37
▸ KDM4C Q9H3R0 1/20 0.37
▸ MYC P01106 1/20 0.36
▸ ALPL P05186 2/20 0.35
▸ ALKBH3 Q96Q83 1/20 0.35
▸ CASP6 P55212 1/20 0.35
▸ POLB P06746 2/20 0.33
▸ L3MBTL1 Q9Y468 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL696836 0.91 ALDH1A1 (0.46) MAPTALDH1A1KDM4ESMN1; SMN2KMT2A
SCHEMBL11655396 0.87 ALDH1A1 (0.47) MAPTALDH1A1KDM4ESMN1; SMN2KMT2A
SCHEMBL11433868 0.86 ALDH1A1 (0.48) MAPTALDH1A1KDM4ESMN1; SMN2KMT2A
SCHEMBL388048 0.85 MAPT (0.59) MAPTALDH1A1KDM4ESMN1; SMN2KMT2A
SCHEMBL29665085 0.84 ALDH1A1 (0.58) MAPTALDH1A1KDM4ESMN1; SMN2KMT2A
SCHEMBL8942310 0.84 ALDH1A1 (0.58) MAPTALDH1A1KDM4ESMN1; SMN2KMT2A
SCHEMBL9343219 0.84 MAPT (0.44) MAPTALDH1A1KDM4ESMN1; SMN2KMT2A
SCHEMBL5444744 0.84 MAPT (0.49) MAPTALDH1A1KDM4ESMN1; SMN2KMT2A
SCHEMBL11658226 0.83 ALDH1A1 (0.48) MAPTALDH1A1KMT2AGAALMNA
SCHEMBL11658236 0.83 ALDH1A1 (0.48) MAPTALDH1A1KMT2AGAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070033749-A1 Anionic azo dyes and the metal complexes thereof ofr colouring leather BASF AKTIENGESELLSCHAFT (DE) 2007-02-15 — — US disclosed
EP-1636413-A1 ANIONIC AZO DYES AND THE METAL COMPLEXES THEREOF OFR COLOURING LEATHER BASF AKTIENGESELLSCHAFT (DE) 2006-03-22 — — EP disclosed
WO-2004109009-A1 ANIONIC AZO DYES AND THE METAL COMPLEXES THEREOF OFR COLOURING LEATHER BASF AKTIENGESELLSCHAFT (DE) 2004-12-16 — — WO disclosed
US-6177552-B1 CONTAINING (((VINYLSULFONYL)ALKYLAMINO)ALKYLSULFONYL)PHENYLAZO GROUPS DYSTARTEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2001-01-23 — — US disclosed
EP-0309406-B2 Reactive dyes, their preparation and their use CIBA SC HOLDING AG (CH) 2000-07-12 — — EP disclosed
EP-0838504-B1 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof DYSTAR TEXTILFARBEN GMBH & CO (DE) 2000-06-07 — — EP disclosed
US-6060591-A FOR DYEING A MATERIAL CONTAINING HYDROXY OR CARBOXAMIDE GROUPS OR BOTH DY STAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND K.G. (DE) 2000-05-09 — — US disclosed
US-5834601-A DYEING CELLULOSE, WOOL, POLYAMIDE DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 1998-11-10 — — US disclosed
EP-0848042-A2 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 1998-06-17 — — EP disclosed
EP-0838504-A1 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 1998-04-29 — — EP disclosed
US-4229171-A Process for the preparation of fiber-reactive dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1980-10-21 — — US disclosed
EP-0016931-A2 Reactive azo dyestuffs, their use in dyeing and printing materials containing amide or hydroxyl groups BAYER AG (DE) 1980-10-15 — — EP disclosed
US-4225492-A Water-soluble disazo dyestuffs, prepared from unsymmetrical heterocyclic diamines CASSELLA AKTIENGESELLSCHAFT (DE) 1980-09-30 — — US disclosed
US-4144231-A Soluble trisazo dyestuffs containing a 2-phenyl-benzimidazolyl, -benzoxazolyl or -benzthiazolyl middle component CASSELLA AKTIENGESELLSCHAFT (DE) 1979-03-13 — — US disclosed
US-4116624-A DISAZO DYES FOR NATURAL OR SYNTHETIC POLYAMIDES CIBA-GEIGY CORPORATION (US) 1978-09-26 — — US disclosed
US-RE29585-E DYEING WOOL CIBA-GEIGY CORPORATION (US) 1978-03-21 — — US disclosed
US-4051118-A Water-soluble disazo dyestuffs containing a 3- or 4-[pyrazolylene-(1)-benzoylamino]-6-sulphophenyl moiety CIBA-GEIGY AG (CH) 1977-09-27 — — US disclosed
US-4045428-A Water-soluble reactive naphthylazonaphthyl dyestuffs HOECHST AKTIENGESELLSCHAFT (DT) 1977-08-30 — — US disclosed
US-3971738-A Heavy metal complexes of azo compounds containing a halogeno-2,3-dihydroxy pyridine coupling component CIBA-GEIGY AG (CH) 1976-07-27 — — US disclosed
US-3933785-A Azo compounds CIBA-GEIGY AG (CH) 1976-01-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070033749-A1 Anionic azo dyes and the metal complexes thereof ofr colouring leather IK, HLA-A, HLA-C MAPT 1887/4885ALDH1A1 1098/4885KDM4E 896/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.