SCHEMBL388048

SCHEMBL388048

Cc1cc(=O)n(-c2ccccc2S(=O)(=O)O)[nH]1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.59
ALDH1A1 P00352 7/20 0.59
KDM4E B2RXH2 6/20 0.59
SMN1; SMN2 Q16637 2/20 0.59
MYC P01106 1/20 0.51
KMT2A Q03164 5/20 0.46
GAA P10253 2/20 0.46
HTT P42858 2/20 0.46
MEN1 O00255 1/20 0.46
TDP1 Q9NUW8 2/20 0.43
ALKBH3 Q96Q83 1/20 0.43
LMNA P02545 2/20 0.41
RECQL P46063 1/20 0.41
MPL P40238 5/20 0.40
KDM5A P29375 1/20 0.39
KDM2B Q8NHM5 1/20 0.39
KDM4C Q9H3R0 1/20 0.39
L3MBTL1 Q9Y468 4/20 0.37
POLB P06746 3/20 0.37
ALOX15 P16050 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11449496 0.86 ALDH1A1 (0.50) MAPTALDH1A1KDM4ESMN1; SMN2MYC
SCHEMBL5447378 0.85 MAPT (0.46) MAPTALDH1A1KDM4ESMN1; SMN2MYC
SCHEMBL9343219 0.84 MAPT (0.44) MAPTALDH1A1KDM4ESMN1; SMN2MYC
SCHEMBL10651976 0.84 ALDH1A1 (0.47) MAPTALDH1A1KDM4ESMN1; SMN2MYC
SCHEMBL10789498 0.83 ALDH1A1 (0.44) MAPTALDH1A1KDM4ESMN1; SMN2MYC
SCHEMBL696836 0.82 ALDH1A1 (0.46) MAPTALDH1A1KDM4ESMN1; SMN2MYC
SCHEMBL9784353 0.82 MAPT (0.52) MAPTALDH1A1KDM4ESMN1; SMN2MYC
SCHEMBL11297520 0.81 ALDH1A1 (0.51) MAPTALDH1A1KDM4ESMN1; SMN2KMT2A
SCHEMBL7840819 0.81 MAPT (0.44) MAPTALDH1A1KDM4ESMN1; SMN2KMT2A
SCHEMBL699689 0.80 MAPT (0.43) MAPTALDH1A1KDM4ESMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4759702-B2 2011-08-31 JP claimed
US-7723494-B2 Yellow anionic disazo dyes CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-05-25 US claimed
US-20080114158-A1 Yellow anionic disazo dyes LENNARTZ MICHAEL 2008-05-15 US claimed
US-20050172420-A1 Yellow anionic disazo dyes CIBA SPECIALTY CHEMICALS CORP. 2005-08-11 US claimed
EP-1509574-A1 YELLOW ANIONIC DISAZO DYES Ciba SC Holding AG (CH) 2005-03-02 EP claimed
WO-2003104333-A1 YELLOW ANIONIC DISAZO DYES CIBA SPECIALTY CHEMICALS HOLDING, INC. (CH) 2003-12-18 WO claimed
EP-0397190-B1 Azoic pigments, their production and their use SYNTHESIA AKCIOVA SPOLECNOST (CZ) 1994-12-07 EP claimed
EP-0397190-A1 Azoic pigments, their production and their use SYNTHESIA akciová spolecnost (CZ) 1990-11-14 EP claimed
EP-2569629-A1 DETECTION OF NICOTINE METABOLITES GFC Diagnostics Ltd. (GB) 2013-03-20 EP disclosed
US-8101731-B2 Yellow anionic disazo dyes CIBA SPECIALTY CHEMICALS CORPORATION 2012-01-24 US disclosed
WO-2011141712-A1 DETECTION OF NICOTINE METABOLITES GFC DIAGNOSTICS LTD. (GB) 2011-11-17 WO disclosed
US-20100199443-A1 YELLO ANIONIC DISAZO DYES LENNARTZ MICHAEL 2010-08-12 US disclosed
US-7723494-B2 Yellow anionic disazo dyes CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-05-25 US disclosed
US-20080114158-A1 Yellow anionic disazo dyes LENNARTZ MICHAEL 2008-05-15 US disclosed
US-4180503-A FOR DYEING POLYAMIDES BAYER AKTIENGESELLSCHAFT (DE) 1979-12-25 US disclosed
US-4144231-A Soluble trisazo dyestuffs containing a 2-phenyl-benzimidazolyl, -benzoxazolyl or -benzthiazolyl middle component CASSELLA AKTIENGESELLSCHAFT (DE) 1979-03-13 US disclosed
US-4143033-A WATER-SOLUBLE DISAZO DYESTUFFS CONTAINING A 2-PHENYL-BENZIMIDAZOLYL,-BENZOXAZOLYL OR-BENZTHIAZOLYL MIDDLE COMPONENT CASSELLA AKTIENGESELLSCHAFT (DE) 1979-03-06 US disclosed
US-4137228-A HIGH TINCTORIAL STRENGTH, COLORFASTNESS CASSELLA AKTIENGESELLSCHAFT (DE) 1979-01-30 US disclosed
US-4124581-A FOR NATURAL AND SYNTHETIC FIBERS, COLORFAST BAYER AKTIENGESELLSCHAFT (DE) 1978-11-07 US disclosed
US-4058516-A DISAZO DYES SANDOZ LTD. (CH) 1977-11-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050172420-A1 Yellow anionic disazo dyes IK, CYB5R3, DCXR MAPT 2297/4885ALDH1A1 3371/4885KDM4E 2336/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.