Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 4/20 | 0.35 |
| ▸ | IDH2 | P48735 | 2/20 | 0.35 |
| ▸ | RBP4 | P02753 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 3/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14430549 | 0.77 | TRPV1 (0.36) | RBP4P2RX7 | |
| SCHEMBL3713355 | 0.72 | HTR2A (0.33) | HTR2CHTR2AHTR2B | |
| SCHEMBL10279750 | 0.72 | PDE4D (0.42) | — | |
| SCHEMBL5439370 | 0.69 | PDE10A (0.31) | — | |
| SCHEMBL17710264 | 0.67 | RBP4 (0.43) | IDH1IDH2RBP4HTR2CHTR2A | |
| SCHEMBL5447564 | 0.66 | MEN1 (0.30) | — | |
| SCHEMBL28234526 | 0.62 | RBP4 (0.42) | IDH1IDH2RBP4HTR2CHTR2A | |
| SCHEMBL20094342 | 0.61 | XPO1 (0.35) | RBP4MALT1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL15094782 | 0.60 | IDH1 (0.48) | IDH1IDH2P2RX7GABRA1GABRG2 | |
| SCHEMBL5444175 | 0.59 | TRPV1 (0.35) | P2RX7HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070179295-A1 | Triazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2007-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070179295-A1 | Triazolopyrimidines | QDPR, DPYD, CYP1B1 | IDH1 328/4885IDH2 304/4885RBP4 3044/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.