Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | CES1 | P23141 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5450543 | 0.86 | TSHR (0.69) | TDP1SRD5A2MEN1KMT2ACES1 | |
| SCHEMBL5443855 | 0.84 | ALDH1A1 (0.56) | SRD5A2MEN1KMT2ACES1CA1 | |
| 4-Nitrobenzoic Acid SCHEMBL43476 | 0.82 | TDP1 (1.00) | TDP1SRD5A2MEN1KMT2ACES1 | |
| Terephthalic Acid SCHEMBL28023943 | 0.82 | TDP1 (1.00) | TDP1SRD5A2MEN1KMT2ACES1 | |
| 4-Nitrobenzoic Acid SCHEMBL10439552 | 0.80 | TDP1 (0.95) | TDP1SRD5A2MEN1KMT2ACES1 | |
| 4-Nitrobenzoic Acid SCHEMBL321099 | 0.80 | TDP1 (0.95) | TDP1SRD5A2MEN1KMT2ACES1 | |
| 4-Nitrobenzoic Acid SCHEMBL9316553 | 0.80 | TDP1 (0.95) | TDP1SRD5A2MEN1KMT2ACES1 | |
| 4-Nitrobenzoic Acid SCHEMBL1566327 | 0.80 | TDP1 (0.95) | TDP1SRD5A2MEN1KMT2ACES1 | |
| 4-Nitrobenzoic Acid SCHEMBL10720762 | 0.80 | TDP1 (0.95) | TDP1SRD5A2MEN1KMT2ACES1 | |
| 4-Nitrobenzoic Acid SCHEMBL8025368 | 0.80 | TDP1 (0.95) | TDP1SRD5A2MEN1KMT2ACES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070123586-A1 | Nitroso derivatives of diphenylamine | MERCK PATENT GMBH (DE) | 2007-05-31 | — | — | US | claimed |
| EP-1687260-A1 | NITROSO DERIVATIVES OF DIPHENYLAMINE | MERCK PATENT GmbH (DE) | 2006-08-09 | — | — | EP | claimed |
| WO-2005051896-A1 | NITROSO DERIVATIVES OF DIPHENYLAMINE | MERCK PATENT GMBH (DE) | 2005-06-09 | — | — | WO | claimed |
| US-20070123586-A1 | Nitroso derivatives of diphenylamine | MERCK PATENT GMBH (DE) | 2007-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070123586-A1 | Nitroso derivatives of diphenylamine | NOS3, CBR3, CBR1 | TDP1 2421/4885SRD5A2 605/4885MEN1 2301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.