Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 18/20 | 0.86 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14491028 | 1.00 | CRHR1 (0.86) | CRHR1 | |
| SCHEMBL14491029 | 0.92 | CRHR1 (0.88) | CRHR1 | |
| SCHEMBL5441707 | 0.92 | CRHR1 (0.84) | CRHR1 | |
| SCHEMBL5445010 | 0.92 | CRHR1 (0.91) | CRHR1 | |
| SCHEMBL14491030 | 0.92 | CRHR1 (0.84) | CRHR1 | |
| SCHEMBL14502313 | 0.91 | CRHR1 (0.73) | CRHR1 | |
| SCHEMBL14491027 | 0.88 | CRHR1 (0.69) | CRHR1 | |
| SCHEMBL5872522 | 0.87 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL5445005 | 0.86 | CRHR1 (0.69) | CRHR1 | |
| SCHEMBL5872519 | 0.82 | CRHR1 (0.76) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070129382-A1 | Crf receptor antagonists, their preparations, their pharmaceutical composition, and their uses | SB PHARMCO PUERTO RICO (PR) | 2007-06-07 | — | — | US | claimed |
| EP-1722826-A2 | CRF RECEPTOR ANTAGONISTS, THEIR PREPARATIONS, THEIR PHARMACEUTICAL COMPOSITION AND THEIR USES | SB Pharmco Puerto Rico Inc. (PR) | 2006-11-22 | — | — | EP | claimed |
| WO-2005079868-A2 | CRF RECEPTOR ANTAGONISTS, THEIR PREPARATIONS, THEIR PHARMACEUTICAL COMPOSITION AND THEIR USES | SB PHARMCO PUERTO RICO INC (US) | 2005-09-01 | — | — | WO | claimed |
| US-20070129382-A1 | Crf receptor antagonists, their preparations, their pharmaceutical composition, and their uses | SB PHARMCO PUERTO RICO (PR) | 2007-06-07 | — | — | US | disclosed |
| US-20070129382-A1 | Crf receptor antagonists, their preparations, their pharmaceutical composition, and their uses | SB PHARMCO PUERTO RICO (PR) | 2007-06-07 | — | — | US | disclosed |
| US-20070129382-A1 | Crf receptor antagonists, their preparations, their pharmaceutical composition, and their uses | SB PHARMCO PUERTO RICO (PR) | 2007-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129382-A1 | Crf receptor antagonists, their preparations, their pharmaceutical composition, and their uses | CRH, CRHR1, CRHR2 | CRHR1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.