Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3301820 | 0.82 | HDAC1 (0.32) | TSHR | |
| SCHEMBL160311 | 0.81 | ALDH1A1 (0.46) | SLC6A2HTR2ASLC6A4SLC6A3TSHR | |
| SCHEMBL27755603 | 0.79 | ALDH1A1 (0.44) | SLC6A2HTR2ASLC6A4SLC6A3TSHR | |
| SCHEMBL28636919 | 0.79 | ALDH1A1 (0.44) | SLC6A2HTR2ASLC6A4SLC6A3TSHR | |
| SCHEMBL28558829 | 0.79 | ALDH1A1 (0.44) | SLC6A2HTR2ASLC6A4SLC6A3TSHR | |
| SCHEMBL4658283 | 0.74 | CHRNB2 (0.39) | TSHRALDH1A1 | |
| SCHEMBL28094321 | 0.74 | SMN1; SMN2 (0.41) | TSHRALDH1A1 | |
| SCHEMBL5391395 | 0.73 | ALDH1A1 (0.30) | TSHRALDH1A1 | |
| SCHEMBL28750369 | 0.73 | CHRNB2 (0.38) | TSHRALDH1A1 | |
| SCHEMBL996139 | 0.72 | HRH3 (0.39) | SLC6A2SLC6A4ADRA1ASLC6A3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070072911-A1 | Indoles and azaindoles as antiviral agents | AVOLIO SALVATORE | 2007-03-29 | — | — | US | disclosed |
| CN-1863528-A | Indoles and azaindoles as antiviral agents | ANGELETTI P IST RICHERCHE BIO (IT) | 2006-11-15 | — | — | CN | disclosed |
| EP-1673081-A1 | INDOLES AND AZAINDOLES AS ANTIVIRAL AGENTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2006-06-28 | — | — | EP | disclosed |
| WO-2005034941-A1 | INDOLES AND AZAINDOLES AS ANTIVIRAL AGENTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IT) | 2005-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070072911-A1 | Indoles and azaindoles as antiviral agents | IDO1, IDO2, NAT1 | ADRA2B 169/4885ADRA2C 75/4885SLC6A2 620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.