Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | CRHBP | P24387 | 1/20 | 0.57 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.53 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.53 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5451487 | 0.88 | ALDH1A1 (0.70) | ALDH1A1LMNAHTTMAPTHPGD | |
| SCHEMBL31337154 | 0.86 | ALDH1A1 (0.65) | ALDH1A1LMNAHTTMAPTHPGD | |
| SCHEMBL23412864 | 0.86 | KMT2A (0.67) | ALDH1A1LMNAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL30092969 | 0.86 | KMT2A (0.67) | ALDH1A1LMNAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL5463741 | 0.86 | ALDH1A1 (0.67) | ALDH1A1LMNAHTTMAPTHPGD | |
| SCHEMBL5442317 | 0.84 | HTT (0.70) | ALDH1A1LMNAHTTMAPTHPGD | |
| SCHEMBL5452848 | 0.83 | ALDH1A1 (0.79) | ALDH1A1LMNAHTTMAPTHPGD | |
| SCHEMBL5446534 | 0.79 | ALDH1A1 (0.66) | ALDH1A1LMNAHTTMAPTHPGD | |
| SCHEMBL11504521 | 0.77 | MAPT (0.67) | ALDH1A1LMNAHTTMAPTSMN1; SMN2 | |
| SCHEMBL1935766 | 0.76 | GAA (0.70) | ALDH1A1LMNAHTTMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |