Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.79 |
| ▸ | LMNA | P02545 | 1/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.69 |
| ▸ | MEN1 | O00255 | 5/20 | 0.69 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5463741 | 0.86 | ALDH1A1 (0.67) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL5451487 | 0.84 | ALDH1A1 (0.70) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL5448140 | 0.83 | ALDH1A1 (0.69) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL5972347 | 0.80 | MAPT (0.77) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL16730430 | 0.78 | MAPT (0.72) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL5448159 | 0.77 | ALDH1A1 (0.66) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL29654104 | 0.76 | EPHX1 (0.72) | ALDH1A1LMNAKMT2AMEN1EPHX1 | |
| SCHEMBL5529555 | 0.76 | EPHX1 (0.72) | ALDH1A1LMNAKMT2AMEN1EPHX1 | |
| SCHEMBL14242999 | 0.75 | CYP19A1 (0.58) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL11609630 | 0.74 | HTT (0.60) | ALDH1A1LMNAKMT2AMEN1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |