Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 3/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.70 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.70 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.70 |
| ▸ | DPP4 | P27487 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.70 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.70 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.70 |
| ▸ | GAPDH | P04406 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | STAT6 | P42226 | 1/20 | 0.70 |
| ▸ | PI4KA | P42356 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.70 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.70 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.70 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.70 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8820093 | 0.95 | ADORA1 (0.66) | ADORA1SMN1; SMN2ADORA3ADORA2AADORA2B | |
| SCHEMBL1238629 | 0.94 | ADORA1 (0.65) | ADORA1SMN1; SMN2ADORA3ADORA2AADORA2B | |
| SCHEMBL13268716 | 0.91 | ADK (0.64) | ADORA1SMN1; SMN2ADORA3ADORA2AADORA2B | |
| SCHEMBL7803298 | 0.86 | ADORA1 (0.76) | ADORA1SMN1; SMN2ADORA3ADORA2AADORA2B | |
| SCHEMBL2040670 | 0.86 | ADORA1 (0.76) | ADORA1SMN1; SMN2ADORA3ADORA2AADORA2B | |
| SCHEMBL5024895 | 0.86 | ADORA1 (0.76) | ADORA1SMN1; SMN2ADORA3ADORA2AADORA2B | |
| SCHEMBL10997946 | 0.86 | ADORA1 (0.76) | ADORA1SMN1; SMN2ADORA3ADORA2AADORA2B | |
| SCHEMBL481524 | 0.86 | ADORA1 (0.76) | ADORA1SMN1; SMN2ADORA3ADORA2AADORA2B | |
| SCHEMBL12963362 | 0.86 | ADORA1 (0.76) | ADORA1SMN1; SMN2ADORA3ADORA2AADORA2B | |
| SCHEMBL17440176 | 0.86 | ADORA1 (0.76) | ADORA1SMN1; SMN2ADORA3ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070178572-A1 | Protein crystal structure | MEDICAL RESEARCH COUNCIL (GB) | 2007-08-02 | — | — | US | claimed |
| EP-1585816-A2 | CRYSTAL STRUCTURE OF THE SET 7/9 HISTONE METHYL TRANSFERASE ACTIVE CATALYTIC DOMAIN AND USES THEREOF | Medical Research Council (GB) | 2005-10-19 | — | — | EP | claimed |
| WO-2004065592-A2 | THE CRYSTAL STRUCTURE OF A CATALYTICALLY ACTIVE PORTION OF A SET 7/9 HISTONE METHYLTRANSFERASE AND USES THEREOF | MEDICAL RESEARCH COUNCIL (GB) | 2004-08-05 | — | — | WO | claimed |
| US-20070178572-A1 | Protein crystal structure | MEDICAL RESEARCH COUNCIL (GB) | 2007-08-02 | — | — | US | disclosed |
| EP-1585816-A2 | CRYSTAL STRUCTURE OF THE SET 7/9 HISTONE METHYL TRANSFERASE ACTIVE CATALYTIC DOMAIN AND USES THEREOF | Medical Research Council (GB) | 2005-10-19 | — | — | EP | disclosed |
| WO-2004065592-A2 | THE CRYSTAL STRUCTURE OF A CATALYTICALLY ACTIVE PORTION OF A SET 7/9 HISTONE METHYLTRANSFERASE AND USES THEREOF | MEDICAL RESEARCH COUNCIL (GB) | 2004-08-05 | — | — | WO | disclosed |