Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 4/20 | 0.31 |
| ▸ | HTR1D | P28221 | 3/20 | 0.31 |
| ▸ | HTR1B | P28222 | 3/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5450705 | 0.91 | HTR1A (0.37) | HTR6HTR1AHTR1DHTR1BCYP1A2 | |
| SCHEMBL11452189 | 0.91 | HTR2A (0.32) | HTR6HTR1AHTR1DHTR1BCYP1A2 | |
| SCHEMBL5459923 | 0.90 | HTR1A (0.39) | HTR1AHTR1DHTR1BCYP1A2CYP3A4 | |
| SCHEMBL5453435 | 0.89 | DPP4 (0.30) | — | |
| SCHEMBL5444828 | 0.89 | HTR2A (0.41) | HTR1AHTR1DHTR1BCYP1A2CYP3A4 | |
| SCHEMBL5450681 | 0.89 | HTR2A (0.41) | HTR1AHTR1DHTR1BCYP1A2CYP3A4 | |
| SCHEMBL5450694 | 0.89 | HTR2A (0.41) | HTR1AHTR1DHTR1BCYP1A2CYP3A4 | |
| SCHEMBL5460080 | 0.89 | HTR2A (0.41) | HTR1AHTR1DHTR1BCYP1A2CYP3A4 | |
| SCHEMBL5466830 | 0.89 | HTR2A (0.41) | HTR1AHTR1DHTR1BCYP1A2CYP3A4 | |
| SCHEMBL5465486 | 0.89 | HTR2A (0.41) | HTR1AHTR1DHTR1BCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8796193-B2 | Refrigerating machine oil compositions | NIPPON OIL CORPORATION (JP) | 2014-08-05 | — | — | US | disclosed |
| US-20070155635-A1 | Refrigerating machine oil compositions | NIPPON OIL CORPORATION (JP) | 2007-07-05 | — | — | US | disclosed |