Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.39 |
| ▸ | HTR1D | P28221 | 7/20 | 0.39 |
| ▸ | HTR1B | P28222 | 7/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 9/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5449271 | 0.99 | HTR2A (0.41) | HTR1AHTR1DHTR1BHTR2AMAPT | |
| SCHEMBL5450694 | 0.99 | HTR2A (0.41) | HTR1AHTR1DHTR1BHTR2AMAPT | |
| SCHEMBL5444828 | 0.99 | HTR2A (0.41) | HTR1AHTR1DHTR1BHTR2AMAPT | |
| SCHEMBL5450681 | 0.99 | HTR2A (0.41) | HTR1AHTR1DHTR1BHTR2AMAPT | |
| SCHEMBL5460080 | 0.99 | HTR2A (0.41) | HTR1AHTR1DHTR1BHTR2AMAPT | |
| SCHEMBL5466830 | 0.99 | HTR2A (0.41) | HTR1AHTR1DHTR1BHTR2AMAPT | |
| SCHEMBL5465486 | 0.99 | HTR2A (0.41) | HTR1AHTR1DHTR1BHTR2AMAPT | |
| SCHEMBL5450705 | 0.96 | HTR1A (0.37) | HTR1AHTR1DHTR1BHTR2AMAPT | |
| SCHEMBL5455693 | 0.90 | HTR1A (0.34) | HTR1AHTR1DHTR1BHTR2AMAPT | |
| SCHEMBL5448239 | 0.90 | HTR6 (0.32) | HTR1AHTR1DHTR1BMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8796193-B2 | Refrigerating machine oil compositions | NIPPON OIL CORPORATION (JP) | 2014-08-05 | — | — | US | disclosed |
| US-20070155635-A1 | Refrigerating machine oil compositions | NIPPON OIL CORPORATION (JP) | 2007-07-05 | — | — | US | disclosed |