Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.86 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.86 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.80 |
| ▸ | MEN1 | O00255 | 7/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.80 |
| ▸ | CA1 | P00915 | 2/20 | 0.80 |
| ▸ | CA2 | P00918 | 2/20 | 0.80 |
| ▸ | CA9 | Q16790 | 1/20 | 0.80 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | P2RX5 | Q93086 | 1/20 | 0.69 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.69 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.69 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | STAT1 | P42224 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5450571 | 0.93 | MAPT (0.76) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL5455565 | 0.93 | MAPT (0.76) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL2350357 | 0.91 | MAPT (0.77) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL3057932 | 0.91 | MAPT (0.73) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL13454573 | 0.89 | CA1 (0.78) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL16587382 | 0.89 | MAPT (0.75) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL18606684 | 0.89 | CA1 (1.00) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL5453548 | 0.87 | MAPT (0.67) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL5462203 | 0.84 | MAPT (0.79) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL17066681 | 0.84 | GPR55 (0.76) | MAPTKDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |