Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 15/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.78 |
| ▸ | MEN1 | O00255 | 4/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.78 |
| ▸ | HPGD | P15428 | 2/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.78 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.78 |
| ▸ | GAA | P10253 | 3/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.71 |
| ▸ | NPC1 | O15118 | 1/20 | 0.71 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.71 |
| ▸ | RAB9A | P51151 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5448244 | 0.84 | MAPT (0.86) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL5448142 | 0.83 | MAPT (1.00) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL5450571 | 0.78 | MAPT (0.76) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL5455565 | 0.78 | MAPT (0.76) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL4690699 | 0.78 | MAPT (0.71) | MAPTALDH1A1KMT2ACYP2C9TDP1 | |
| SCHEMBL4517204 | 0.77 | MAPT (0.77) | MAPTALDH1A1CYP2C9NPC1RAB9A | |
| SCHEMBL3057932 | 0.76 | MAPT (0.73) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL2350357 | 0.76 | MAPT (0.77) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL85548 | 0.76 | AKR1C3 (0.71) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL2918462 | 0.76 | MAPT (0.69) | MAPTALDH1A1MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |