SCHEMBL5448281

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14313850	0.96	DGKA (0.47)	DGKAALDH1A1CNR1CNR2FAAH
	SCHEMBL1782243	0.91	DGKA (0.46)	DGKAALDH1A1CNR1CNR2FAAH
	SCHEMBL9073956	0.90	USP2 (0.47)	FFAR1FFAR4MEN1MAPTKMT2A
	SCHEMBL17237503	0.90	USP2 (0.47)	FFAR1FFAR4MEN1MAPTKMT2A
	SCHEMBL17237494	0.90	USP2 (0.47)	FFAR1FFAR4MEN1MAPTKMT2A
	SCHEMBL17237492	0.90	USP2 (0.47)	FFAR1FFAR4MEN1MAPTKMT2A
	SCHEMBL11656416	0.88	USP2 (0.44)	FFAR4MEN1MAPTKMT2AGMNN
	SCHEMBL28862599	0.85	ALDH1A1 (0.56)	DGKAALDH1A1CNR1CNR2FAAH
	SCHEMBL28342030	0.85	DGKA (0.55)	DGKAALDH1A1CNR1CNR2FAAH
	SCHEMBL17237493	0.83	USP2 (0.41)	ALDH1A1MEN1MAPTKMT2AGMNN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.