Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.71 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | UBE2N | P61088 | 3/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.63 |
| ▸ | CFTR | P13569 | 1/20 | 0.61 |
| ▸ | RAB7A | P51149 | 2/20 | 0.59 |
| ▸ | FLT3 | P36888 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16451342 | 0.79 | CFTR (0.70) | CFTR | |
| SCHEMBL5444948 | 0.78 | FLT3 (0.70) | KMT2AMEN1RAB9ACFTRFLT3 | |
| SCHEMBL5447685 | 0.77 | MEN1 (1.00) | KMT2AMEN1UBE2NNPC1RAB9A | |
| SCHEMBL5447655 | 0.77 | FLT3 (0.65) | KMT2AMEN1RAB9AFLT3ALDH1A1 | |
| SCHEMBL5453513 | 0.75 | FLT3 (0.62) | KMT2AMEN1RAB9AFLT3ALDH1A1 | |
| SCHEMBL5451474 | 0.75 | ALDH1A1 (0.72) | KMT2AMEN1UBE2NNPC1RAB9A | |
| SCHEMBL19879834 | 0.75 | CFTR (0.71) | KMT2AMEN1UBE2NNPC1RAB9A | |
| SCHEMBL14825265 | 0.75 | CFTR (0.80) | KMT2AMEN1UBE2NNPC1RAB9A | |
| SCHEMBL5467164 | 0.74 | FLT3 (0.54) | KMT2AMEN1RAB9ACFTRFLT3 | |
| SCHEMBL5450973 | 0.73 | FLT3 (0.67) | KMT2AMEN1RAB9ACFTRFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | GPC BIOTECH AG (DE) | 2007-11-29 | — | — | US | claimed |
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | GPC BIOTECH AG (DE) | 2007-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | TBCA, PARK7, NFATC1 | KMT2A 4785/4885MEN1 2891/4885UBE2N 4748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.