Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 1.00 |
| ▸ | IDO1 | P14902 | 18/20 | 0.78 |
| ▸ | NOS3 | P29474 | 1/20 | 0.77 |
| ▸ | NOS2 | P35228 | 1/20 | 0.77 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3771466 | 0.89 | IDO1 (1.00) | NOS1IDO1NOS3NOS2SLC11A2 | |
| SCHEMBL3321590 | 0.89 | IDO1 (1.00) | NOS1IDO1NOS3NOS2 | |
| SCHEMBL3762941 | 0.89 | IDO1 (1.00) | NOS1IDO1NOS3NOS2SLC11A2 | |
| SCHEMBL3763030 | 0.89 | NOS1 (0.78) | NOS1IDO1NOS3NOS2SLC11A2 | |
| SCHEMBL9198797 | 0.89 | IDO1 (1.00) | NOS1IDO1NOS3NOS2SLC11A2 | |
| SCHEMBL3779731 | 0.89 | IDO1 (1.00) | NOS1IDO1NOS3NOS2SLC11A2 | |
| Benzyl Carbamimidothioate SCHEMBL974745 | 0.87 | IDO1 (1.00) | NOS1IDO1NOS3NOS2SLC11A2 | |
| Bromide SCHEMBL5042180 | 0.87 | IDO1 (0.96) | NOS1IDO1NOS3NOS2 | |
| Bromide SCHEMBL4910420 | 0.87 | IDO1 (0.96) | NOS1IDO1NOS3NOS2SLC11A2 | |
| Hydrochloric Acid SCHEMBL3815185 | 0.87 | IDO1 (1.00) | NOS1IDO1NOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670720-A1 | ENZYME INHIBITORS | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-09-13 | — | — | EP | claimed |
| WO-1994012165-A2 | ENZYME INHIBITORS | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-06-09 | — | — | WO | claimed |
| CN-101129295-B | There is the binary initiator system of good storage stability and especially suitable for acidic system | HERAEUS KULZER GMBH (DE) | 2016-02-10 | — | — | CN | disclosed |
| CN-101129295-A | 2-component initiator system (amine free) with storage stability and especially suitable for acidic systems | HERAEUS KULZER GMBH (DE) | 2008-02-27 | — | — | CN | disclosed |
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |