Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 15/20 | 1.00 |
| ▸ | NOS1 | P29475 | 3/20 | 0.78 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.65 |
| ▸ | NOS3 | P29474 | 2/20 | 0.63 |
| ▸ | NOS2 | P35228 | 2/20 | 0.63 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5042180 | 0.98 | IDO1 (0.96) | IDO1NOS1TAAR1NOS3NOS2 | |
| SCHEMBL5450413 | 0.89 | NOS1 (1.00) | IDO1NOS1NOS3NOS2SLC11A2 | |
| SCHEMBL9198797 | 0.83 | IDO1 (1.00) | IDO1NOS1NOS3NOS2SLC11A2 | |
| SCHEMBL3680445 | 0.81 | IDO1 (0.68) | IDO1NOS1TAAR1NOS3NOS2 | |
| SCHEMBL29271495 | 0.81 | IDO1 (0.68) | IDO1NOS1TAAR1 | |
| SCHEMBL15457424 | 0.80 | IDO1 (0.67) | IDO1NOS1TAAR1NOS3NOS2 | |
| Bromide SCHEMBL4006714 | 0.79 | TAAR1 (0.66) | IDO1NOS1TAAR1NOS3NOS2 | |
| SCHEMBL3779731 | 0.78 | IDO1 (1.00) | IDO1NOS1NOS3NOS2SLC11A2 | |
| SCHEMBL3763030 | 0.78 | NOS1 (0.78) | IDO1NOS1NOS3NOS2SLC11A2 | |
| SCHEMBL3321590 | 0.78 | IDO1 (1.00) | IDO1NOS1NOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075177-A2 | ANTIBIOTICS TARGETING MREB | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2007-07-05 | — | — | WO | claimed |
| US-20060241185-A1 | Antibiotics targeting MreB | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2006-10-26 | — | — | US | claimed |
| US-20190119436-A1 | ANTIMICROBIAL POLYMERIC PARTICLES | BAR-ILAN RESEARCH & DEVELOPMENT COMPANY LTD (IL) | 2019-04-25 | — | — | US | disclosed |
| US-9656953-B2 | Inhibition of cell proliferation | UNIVERSITY OF SOUTH FLORIDA (US) | 2017-05-23 | — | — | US | disclosed |
| US-9656953-B2 | Inhibition of cell proliferation | UNIVERSITY OF SOUTH FLORIDA (US) | 2017-05-23 | — | — | US | disclosed |
| US-20140221658-A1 | INHIBITION OF CELL PROLIFERATION | UNIVERSITY OF SOUTH FLORIDA (US) | 2014-08-07 | — | — | US | disclosed |
| US-20140221658-A1 | INHIBITION OF CELL PROLIFERATION | UNIVERSITY OF SOUTH FLORIDA (US) | 2014-08-07 | — | — | US | disclosed |
| US-8642278-B2 | Inhibition of cell proliferation | UNIVERSITY OF SOUTH FLORIDA (US) | 2014-02-04 | — | — | US | disclosed |
| US-8642278-B2 | Inhibition of cell proliferation | UNIVERSITY OF SOUTH FLORIDA (US) | 2014-02-04 | — | — | US | disclosed |
| US-7855228-B2 | Antibiotics targeting MreB | THE BOARD OF TRUSTEES OF THE LELAND STAMFORD JUNIOR UNIVERSITY (US) | 2010-12-21 | — | — | US | disclosed |
| US-7855228-B2 | Antibiotics targeting MreB | THE BOARD OF TRUSTEES OF THE LELAND STAMFORD JUNIOR UNIVERSITY (US) | 2010-12-21 | — | — | US | disclosed |
| US-7855228-B2 | Antibiotics targeting MreB | THE BOARD OF TRUSTEES OF THE LELAND STAMFORD JUNIOR UNIVERSITY (US) | 2010-12-21 | — | — | US | disclosed |
| CN-1925859-B | 4-(sulfanyl-pyrimidin-4-ylmethyl)-morpholine derivatives and related compounds as GABA receptor ligands for the treatment of anxiety, depression and epilepsy | HOFFMANN LA ROCHE | 2010-11-24 | — | — | CN | disclosed |
| US-20070254318-A1 | INHIBITION OF CELL PROLIFERATION | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-11-01 | — | — | US | disclosed |
| US-20070254318-A1 | INHIBITION OF CELL PROLIFERATION | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-11-01 | — | — | US | disclosed |
| WO-2007075177-A2 | ANTIBIOTICS TARGETING MREB | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2007-07-05 | — | — | WO | disclosed |
| WO-2007062222-A2 | INHIBITION OF CELL PROLIFERATION | UNIVERSITY OF SOUTH FLORIDA (US) | 2007-05-31 | — | — | WO | disclosed |
| CN-1925859-A | 4-(sulfanyl-pyrimidin-4-ylmethyl)-morpholine derivatives and related compounds as GABA receptor ligands for the treatment of anxiety, depression and epilepsy | HOFFMANN LA ROCHE (CH) | 2007-03-07 | — | — | CN | disclosed |
| US-20060241185-A1 | Antibiotics targeting MreB | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2006-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254318-A1 | INHIBITION OF CELL PROLIFERATION | RB1, RAF1, NRAS | IDO1 4187/4885NOS1 3526/4885TAAR1 4545/4885 |
| US-20060241185-A1 | Antibiotics targeting MreB | SMC4, INCENP, DDB1 | IDO1 2985/4885NOS1 4294/4885TAAR1 4402/4885 |
| US-20140221658-A1 | INHIBITION OF CELL PROLIFERATION | RB1, RAF1, NRAS | IDO1 4187/4885NOS1 3526/4885TAAR1 4545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.