Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.48 |
| ▸ | CNR1 | P21554 | 2/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5444900 | 0.82 | CNR1 (0.56) | GPBAR1CNR1PTGS2TP53 | |
| SCHEMBL14339091 | 0.82 | CNR1 (0.44) | GPBAR1CNR1PTGS2TP53 | |
| SCHEMBL5174504 | 0.82 | CNR1 (0.53) | GPBAR1CNR1PTGS2LMNATP53 | |
| SCHEMBL5448796 | 0.74 | CNR1 (0.50) | CNR1PTGS2LMNANPSR1 | |
| SCHEMBL5443076 | 0.71 | CCNE1 (0.45) | CNR1PTGS2LMNATP53 | |
| SCHEMBL5449238 | 0.69 | PTGS2 (0.48) | CNR1PTGS2LMNANPSR1 | |
| SCHEMBL5171605 | 0.68 | GAA (0.51) | CNR1PTGS2LMNATP53 | |
| SCHEMBL2948208 | 0.68 | PTGS2 (0.55) | CNR1PTGS2 | |
| SCHEMBL5169418 | 0.68 | KCNH2 (0.38) | GPBAR1 | |
| SCHEMBL14339087 | 0.67 | CNR1 (0.57) | CNR1PTGS2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070281937-A1 | Ion Channel Modulators | SCION PHARMACEUTICALS, INC. | 2007-12-06 | — | — | US | disclosed |
| US-20070281937-A1 | Ion Channel Modulators | SCION PHARMACEUTICALS, INC. | 2007-12-06 | — | — | US | disclosed |
| US-20070197513-A1 | Ion channel modulators | SCION PHARMACEUTICALS, INC. | 2007-08-23 | — | — | US | disclosed |
| US-20070197513-A1 | Ion channel modulators | SCION PHARMACEUTICALS, INC. | 2007-08-23 | — | — | US | disclosed |
| EP-1723119-A1 | ION CHANNEL MODULATORS | Wyeth a Corporation of the State of Delaware (US) | 2006-11-22 | — | — | EP | disclosed |
| EP-1723117-A2 | ION CHANNEL MODULATORS | Wyeth a Corporation of the State of Delaware (US) | 2006-11-22 | — | — | EP | disclosed |
| WO-2005086836-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2005-09-22 | — | — | WO | disclosed |
| WO-2005087747-A1 | ION CHANNEL MODULATORS | WYETH (US) | 2005-09-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070281937-A1 | Ion Channel Modulators | CACNA1B, CACNA1C, TRPV1 | GPBAR1 420/4885CNR1 293/4885PTGS2 1158/4885 |
| US-20070197513-A1 | Ion channel modulators | CACNA1B, CACNA1C, TRPV1 | GPBAR1 420/4885CNR1 293/4885PTGS2 1158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.