Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5494823 | 0.75 | ALDH1A1 (0.35) | TSHRGAAALDH1A1 | |
| SCHEMBL21847351 | 0.71 | GAA (0.37) | TSHRGAAALDH1A1 | |
| SCHEMBL5606283 | 0.67 | GAA (0.41) | TSHRGAAALDH1A1 | |
| SCHEMBL1270028 | 0.67 | — | — | |
| SCHEMBL8650247 | 0.67 | ALDH1A1 (0.36) | TSHRGAAALDH1A1 | |
| SCHEMBL1289444 | 0.67 | GAA (0.32) | GAAALDH1A1 | |
| SCHEMBL9000767 | 0.65 | — | — | |
| SCHEMBL5688553 | 0.65 | ALDH1A1 (0.35) | TSHRGAAALDH1A1 | |
| SCHEMBL28640671 | 0.65 | GAA (0.35) | GAAALDH1A1 | |
| SCHEMBL5710006 | 0.65 | GAA (0.35) | GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070173935-A1 | Nucleus pulposus augmentation pretreatment technique | DEPUY SPINE, INC. | 2007-07-26 | — | — | US | claimed |
| US-20070173935-A1 | Nucleus pulposus augmentation pretreatment technique | DEPUY SPINE, INC. | 2007-07-26 | — | — | US | disclosed |