SCHEMBL5494823

SCHEMBL5494823

C=CC([SiH3])(OC(C)=O)OC(C)=O

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.35
GAA P10253 1/20 0.34
HSD17B10 Q99714 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5450880 0.75 TSHR (0.32) ALDH1A1GAATSHR
SCHEMBL5606283 0.72 GAA (0.41) ALDH1A1GAAHSD17B10TDP1TSHR
SCHEMBL8650247 0.72 ALDH1A1 (0.36) ALDH1A1GAAHSD17B10TDP1TSHR
SCHEMBL1270028 0.72
SCHEMBL1289444 0.71 GAA (0.32) ALDH1A1GAA
SCHEMBL5688553 0.70 ALDH1A1 (0.35) ALDH1A1GAAHSD17B10TDP1TSHR
SCHEMBL9000767 0.70
SCHEMBL5710006 0.70 GAA (0.35) ALDH1A1GAA
SCHEMBL28640671 0.70 GAA (0.35) ALDH1A1GAA
SCHEMBL1151451 0.69 GAA (0.42) ALDH1A1GAAHSD17B10TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023072128-A1 COLORANT COMPOSITION AND COATED ARTICLE GUANGDONG HUARUN PAINTS CO., LTD. (CN) 2023-05-04 WO claimed
WO-2023072128-A1 COLORANT COMPOSITION AND COATED ARTICLE GUANGDONG HUARUN PAINTS CO., LTD. (CN) 2023-05-04 WO disclosed
CN-114384775-A Toner, external additive for toner, and fine particles 佳能株式会社 2022-04-22 CN disclosed
US-10351675-B2 Compositions and methods for injectable composition for an accommodating instraocular lens ADVENTUS TECHNOLOGY, INC. (US) 2019-07-16 US disclosed
US-20180273687-A1 Compositions and Methods for Injectable Composition for an Accommodating Instraocular Lens ADVENTUS TECHNOLOGY, INC. 2018-09-27 US disclosed
EP-3236884-A1 COMPOSITIONS AND METHODS FOR INJECTABLE COMPOSITION FOR AN ACCOMMODATING INTRAOCULAR LENS Adventus Technology, Inc. (US) 2017-11-01 EP disclosed
WO-2016101025-A1 COMPOSITIONS AND METHODS FOR INJECTABLE COMPOSITION FOR AN ACCOMMODATING INTRAOCULAR LENS BRIEN HOLDEN VISION INSTITUTE (AU) 2016-06-30 WO disclosed
EP-1591264-B9 IMAGE RECORDING SHEET AND METHOD OF IMAGE RECORDING DAICEL CHEM (JP) 2007-10-24 EP disclosed
EP-1591264-B1 IMAGE RECORDING SHEET AND METHOD OF IMAGE RECORDING DAICEL CHEM (JP) 2007-06-06 EP disclosed
EP-1285773-B1 Transfer sheets SEIKO EPSON CORP (JP) 2006-12-27 EP disclosed
EP-1266766-A1 Transfer sheets Daicel Chemical Industries, Ltd. (JP) 2002-12-18 EP disclosed
US-20020160162-A1 Recording sheets and process for the production thereof DAICEL CHEMICAL INDUSTRIES, LTD. 2002-10-31 US disclosed
US-6465078-B1 POLYETHYLENE TEREPHTHALATE SUBSTRATES HAVING CATIONIC COPOLYMER COATINGS, COUPLERS AND HYROPHILIC POLYMERS, USED FOR INK JET PRINTERS DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2002-10-15 US disclosed
US-6455133-B1 STRETCHED STYRENIC SHEET IS TEARABLE; PARTICULATE LUBRICANT; OVERHEAD PROJECTORS; ABSORPTION DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2002-09-24 US disclosed
EP-0956971-B1 Ink-receptor sheet for ink-jet printing and method for producing the same DAICEL CHEM (JP) 2002-07-10 EP disclosed
EP-1114734-A1 RESIN COMPOSITION FOR INK-JET RECORDING SHEET AND RECORDING SHEET MADE WITH THE SAME DAICEL CHEMICAL INDUSTRIES, Ltd. (JP) 2001-07-11 EP disclosed
EP-0989162-A1 THERMOPLASTIC RESIN COMPOSITION, WATER-BASED COMPOSITION, HEAT-SENSITIVE PRESSURE-SENSITIVE ADHESIVE, AND HEAT-SENSITIVE SHEET Daicel Chemical Industries, Ltd. (JP) 2000-03-29 EP disclosed
EP-0989168-A1 Water-based coating composition Daicel Chemical Industries, Ltd. (JP) 2000-03-29 EP disclosed
EP-0956971-A1 Ink-receptor sheet for ink-jet printing and method for producing the same Daicel Chemical Industries, Ltd. (JP) 1999-11-17 EP disclosed
EP-0896883-A1 RECORDING SHEETS AND PROCESS FOR THE PRODUCTION THEREOF DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1999-02-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10351675-B2 Compositions and methods for injectable composition for an accommodating instraocular lens MCM6, INCENP, PSMA6 ALDH1A1 1602/4885GAA 323/4885HSD17B10 2939/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.