Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 7/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.65 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.61 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | CTSV | O60911 | 3/20 | 0.56 |
| ▸ | CTSL | P07711 | 3/20 | 0.56 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.55 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.55 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2341775 | 0.89 | MAPT (0.71) | HCAR3MAPTKMT2AAKR1C3AKR1C2 | |
| SCHEMBL6658894 | 0.85 | MAPT (0.57) | MAPTKMT2AMEN1LMNAGAA | |
| SCHEMBL5580003 | 0.85 | CTSV (0.57) | HCAR3MAPTKMT2AAKR1C3AKR1C2 | |
| SCHEMBL810481 | 0.84 | MAPT (0.55) | MAPTKMT2AAKR1C3AKR1C2MEN1 | |
| SCHEMBL3919788 | 0.83 | MAPK1 (0.63) | MAPTKMT2AMEN1LMNAGAA | |
| SCHEMBL14400495 | 0.83 | MAPT (0.73) | HCAR3MAPTKMT2AAKR1C3AKR1C2 | |
| SCHEMBL2338616 | 0.83 | HCAR3 (1.00) | HCAR3MAPTKMT2AAKR1C3AKR1C2 | |
| SCHEMBL17403333 | 0.82 | MAPT (0.59) | MAPTKMT2AAKR1C3AKR1C2MEN1 | |
| SCHEMBL5444479 | 0.81 | GAA (0.67) | MAPTKMT2AMEN1HPGDGAA | |
| SCHEMBL4498364 | 0.81 | HCAR3 (0.61) | HCAR3MAPTKMT2AAKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070232669-A1 | N-phenylbenzotriazolyl c-kit inhibitors | OSI PHARMACEUTICALS, INC. | 2007-10-04 | — | — | US | disclosed |
| US-20070232669-A1 | N-phenylbenzotriazolyl c-kit inhibitors | OSI PHARMACEUTICALS, INC. | 2007-10-04 | — | — | US | disclosed |
| WO-2007092403-A1 | N-PHENYLBENZOTRIAZOLYL C-KIT INHIBITORS | OSI PHARMACEUTICALS, INC. (US) | 2007-08-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232669-A1 | N-phenylbenzotriazolyl c-kit inhibitors | KIT, CHUK, TNNI3K | HCAR3 3267/4885MAPT 4108/4885KMT2A 297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.