Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | RAF1 | P04049 | 3/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | DDX3X | O00571 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5460458 | 0.81 | P2RY1 (0.47) | CCNCCDK8LMNAMAPTGAA | |
| SCHEMBL5456051 | 0.79 | MAPT (0.49) | CCNCCDK8LMNAMAPTGAA | |
| SCHEMBL5460110 | 0.78 | ALK (0.43) | CCNCCDK8LMNAMAPTGAA | |
| SCHEMBL5459432 | 0.76 | NPY2R (0.43) | LMNAMAPTGAAHSD17B10EPHX2 | |
| SCHEMBL5455740 | 0.75 | DGAT1 (0.40) | CCNCCDK8LMNAMAPTGAA | |
| SCHEMBL5466775 | 0.75 | MAPT (0.45) | LMNAMAPTGAASMN1; SMN2BRAF | |
| SCHEMBL5549272 | 0.75 | MAPT (0.47) | LMNAMAPTSMN1; SMN2NAMPTKDM4E | |
| SCHEMBL5462771 | 0.73 | KDM4E (0.46) | LMNAMAPTGAASMN1; SMN2HSD17B10 | |
| SCHEMBL5458109 | 0.73 | NAMPT (0.58) | LMNAMAPTSMN1; SMN2NAMPTALDH1A1 | |
| SCHEMBL5465407 | 0.72 | TRPV1 (0.46) | LMNAMAPTSMN1; SMN2NAMPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | SANKYO COMPANY, LIMITED (JP) | 2007-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | UGP2, SLC14A1, DGAT1 | CCNC 1693/4885CDK8 4008/4885LMNA 3721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.