Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5460989 | 0.85 | PARP1 (0.69) | PARP1DHODH | |
| SCHEMBL7317874 | 0.85 | PARP1 (1.00) | PARP1DHODH | |
| SCHEMBL5453704 | 0.78 | PARP1 (0.56) | PARP1DHODH | |
| SCHEMBL7318483 | 0.76 | PARP1 (1.00) | PARP1DHODH | |
| SCHEMBL1891860 | 0.75 | PARP1 (0.80) | PARP1DHODH | |
| SCHEMBL8624640 | 0.74 | PARP1 (0.73) | PARP1DHODH | |
| SCHEMBL458836 | 0.71 | PARP1 (1.00) | PARP1DHODH | |
| SCHEMBL29412034 | 0.71 | PARP1 (1.00) | PARP1DHODH | |
| SCHEMBL29412005 | 0.70 | PARP1 (0.74) | PARP1DHODH | |
| SCHEMBL5467831 | 0.70 | PARP1 (0.54) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070072912-A1 | Alicyclic-amine-substituted 4-carboxamido-benzimidazoles as parp-inhibitors and antioxidants | CEDARS-SINAI MEDICAL CENTER (US) | 2007-03-29 | — | — | US | claimed |
| US-20070072912-A1 | Alicyclic-amine-substituted 4-carboxamido-benzimidazoles as parp-inhibitors and antioxidants | CEDARS-SINAI MEDICAL CENTER (US) | 2007-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070072912-A1 | Alicyclic-amine-substituted 4-carboxamido-benzimidazoles as parp-inhibitors and antioxidants | PARP1, PARP2, PARP11 | PARP1 1/4885DHODH 1677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.