Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 14/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5458884 | 1.00 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2ATRPV1MC4R | |
| SCHEMBL5451845 | 1.00 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2ATRPV1MC4R | |
| SCHEMBL5447584 | 0.90 | MC4R (0.42) | MC4R | |
| SCHEMBL5456730 | 0.90 | MC4R (0.42) | MC4R | |
| SCHEMBL5447590 | 0.90 | MC4R (0.42) | MC4R | |
| SCHEMBL5454454 | 0.86 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2ATRPV1MC4R | |
| SCHEMBL5452964 | 0.86 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2ATRPV1MC4R | |
| SCHEMBL5452961 | 0.86 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2ATRPV1MC4R | |
| SCHEMBL5465491 | 0.86 | MC4R (0.40) | ALDH1A1MEN1KMT2ATRPV1MC4R | |
| SCHEMBL5456601 | 0.85 | AVPR1A (0.47) | TRPV1MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070191364-A1 | AMINOPIPERIDINE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2007-08-16 | — | — | US | claimed |
| US-20070191364-A1 | AMINOPIPERIDINE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191364-A1 | AMINOPIPERIDINE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | MC4R, MC5R, TAAR5 | ALDH1A1 344/4885MEN1 1307/4885KMT2A 1421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.