Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11056464 | 0.74 | ALDH1A1 (0.46) | KDM4EDHODHCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5457312 | 0.73 | PRMT5 (0.66) | PRMT5KDM4ECYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL5104145 | 0.71 | PRMT5 (1.00) | PRMT5KDM4EGAATP53TLR8 | |
| SCHEMBL5448072 | 0.71 | PRMT5 (0.64) | PRMT5KDM4EBACE1CYP1A2CYP2D6 | |
| SCHEMBL5025943 | 0.71 | PRMT5 (0.58) | PRMT5KDM4ECYP1A2CYP2D6TLR8 | |
| SCHEMBL15540772 | 0.71 | PIK3CA (0.49) | KDM4EBACE1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL34467155 | 0.71 | HRH4 (0.44) | KDM4EBACE1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL21555506 | 0.71 | HRH4 (0.44) | KDM4EBACE1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5459067 | 0.69 | PRMT5 (0.60) | PRMT5KDM4ECYP3A4ALDH1A1HSD17B10 | |
| SCHEMBL5455913 | 0.69 | PRMT5 (0.60) | PRMT5KDM4ECYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070232673-A1 | 2-Imino-benzimidazoles | ABBOTT LABORATORIES | 2007-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232673-A1 | 2-Imino-benzimidazoles | CYP2C19, UGT2B7, UGT2B17 | PRMT5 2145/4885KDM4E 2704/4885DHODH 789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.