Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5452226 | 1.00 | F10 (0.52) | F10NPC1RAB9APTGS2CNR1 | |
| SCHEMBL5467276 | 0.88 | F10 (0.64) | F10 | |
| SCHEMBL5467272 | 0.88 | F10 (0.64) | F10 | |
| SCHEMBL5458443 | 0.87 | F10 (0.51) | F10PTGS2CNR1CNR2 | |
| SCHEMBL5458437 | 0.87 | F10 (0.51) | F10PTGS2CNR1CNR2 | |
| SCHEMBL5460140 | 0.85 | F10 (0.51) | F10NPC1RAB9APTGS2 | |
| SCHEMBL5473910 | 0.84 | F10 (0.52) | F10PTGS2 | |
| SCHEMBL5473913 | 0.84 | F10 (0.52) | F10PTGS2 | |
| SCHEMBL5466053 | 0.82 | F10 (0.61) | F10PTGS2 | |
| SCHEMBL5466056 | 0.82 | F10 (0.61) | F10PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070265259-A1 | Proline Derivatives | MERCK PATENT GMBH (DE) | 2007-11-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265259-A1 | Proline Derivatives | F2, XPNPEP1, PRAP1 | F10 10/4885NPC1 2226/4885RAB9A 2096/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.