SCHEMBL5467272

SCHEMBL5467272

O=C(Nc1ccc(N2CCOCC2=O)cc1)[C@H]1CCCN1Cc1cc(-c2ccc(Cl)s2)on1

nearest known ligand 0.64

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ F10 P00742 20/20 0.64
▸ F2 P00734 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5467276 1.00 F10 (0.64) F10F2
SCHEMBL5461305 0.89 F10 (0.52) F10F2
SCHEMBL5461311 0.89 F10 (0.52) F10F2
SCHEMBL5452226 0.88 F10 (0.52) F10
SCHEMBL5452229 0.88 F10 (0.52) F10
SCHEMBL5457177 0.85 F10 (0.48) F10
SCHEMBL5462718 0.85 F10 (0.48) F10
SCHEMBL5457182 0.85 F10 (0.48) F10
SCHEMBL5462719 0.85 F10 (0.48) F10
SCHEMBL5460247 0.80 F10 (0.53) F10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070265259-A1 Proline Derivatives MERCK PATENT GMBH (DE) 2007-11-15 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070265259-A1 Proline Derivatives F2, XPNPEP1, PRAP1 F10 10/4885F2 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback