SCHEMBL5452287

SCHEMBL5452287

C=C(C)C(=O)OC(O)=CC

nearest known ligand 0.46

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
TSHR P16473 4/20 0.37
TDP1 Q9NUW8 2/20 0.36
HSD17B10 Q99714 1/20 0.36
THRB P10828 1/20 0.34
ELANE P08246 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2537216 0.79 ALDH1A1 (0.41) ALDH1A1TSHRTDP1HSD17B10THRB
Acetic Acid SCHEMBL28803626 0.78 ALDH1A1 (0.55) ALDH1A1TSHRTDP1HSD17B10THRB
Acetic Acid SCHEMBL2896489 0.78 ALDH1A1 (0.55) ALDH1A1TSHRTDP1HSD17B10THRB
SCHEMBL28018504 0.78 ALDH1A1 (0.44) ALDH1A1TSHRTDP1HSD17B10THRB
SCHEMBL15963 0.78 ALDH1A1 (0.61) ALDH1A1TSHRTDP1HSD17B10THRB
SCHEMBL28170047 0.78 ALDH1A1 (0.61) ALDH1A1TSHRTDP1HSD17B10THRB
SCHEMBL472709 0.78 ALDH1A1 (0.39) ALDH1A1TSHRTDP1HSD17B10THRB
SCHEMBL472712 0.78 ALDH1A1 (0.39) ALDH1A1TSHRTDP1HSD17B10THRB
SCHEMBL6137551 0.77 ALDH1A1 (0.48) ALDH1A1TSHRTDP1HSD17B10THRB
SCHEMBL6137545 0.77 ALDH1A1 (0.48) ALDH1A1TSHRTDP1HSD17B10THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070104962-A1 Hydrophillic polyisocyanate mixtures BAYER MATERIALSCIENCE AG 2007-05-10 US disclosed
US-6777523-B1 POLYETHER-MODIFIED, WATER-DISPERSIBLE POLYISOCYANATE MIXTURES, AS INITIAL COMPONENT IN THE PRODUCTION OF POLYURETHANE PLASTICS, IN PARTICULAR AS CROSSLINKER FOR WATER- SOLUBLE OR WATER-DISPERSIBLE LACQUER BINDING AGENTS BAYER AKTIENGESELLSCHAFT (DE) 2004-08-17 US disclosed
US-6767958-B2 REACTED WITH 2- (CYCLOHEXYLAMINO)-ETHANESULFONIC ACID AND/OR 3-(CYCLOHEXYLAMINO) -ETHANESULFONIC ACID AND/OR 3-(CYCLOHEXYLAMINO) -PROPANESULFONIC ACID; COATINGS BAYER AKTIENGESELLSCHAFT (DE) 2004-07-27 US disclosed
US-20040034162-A1 Modified polyisocyanates COVESTRO DEUTSCHLAND AG (DE) 2004-02-19 US disclosed
US-6426414-B1 REACTING DIISOCYANATOHEXANE WITH POLYOXYETHYLENE GLYCOL FORMING COMPOUNDS/POLYMERS CONTAINING POLYISOCYANURATE GROUPS; FOR USE AS STARTING COMPONENTS IN POLYURETHANE PLASTICS AND CROSSLINKING AGENTS FOR AQUEOUS BINDER COMPOSITIONS BAYER AKTIENGESELLSCHAFT (DE) 2002-07-30 US disclosed