Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.59 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.59 |
| ▸ | RORC | P51449 | 2/20 | 0.58 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6031454 | 0.91 | L3MBTL1 (0.51) | L3MBTL1FFAR1AKR1B1RORCFFAR4 | |
| SCHEMBL11463317 | 0.87 | TRPV1 (0.59) | FFAR1AKR1B1FFAR4RAB9AGFER | |
| SCHEMBL9424921 | 0.86 | FFAR1 (0.76) | L3MBTL1FFAR1FFAR4 | |
| SCHEMBL11653014 | 0.83 | L3MBTL1 (0.86) | L3MBTL1FFAR1FFAR4RAB9ASMN1; SMN2 | |
| SCHEMBL6031251 | 0.82 | FFAR1 (0.49) | L3MBTL1FFAR1AKR1B1RORCFFAR4 | |
| SCHEMBL5447986 | 0.82 | FFAR1 (0.84) | FFAR1AKR1B1RORCFFAR4RAB9A | |
| SCHEMBL3961745 | 0.81 | AKR1B1 (0.81) | L3MBTL1FFAR1AKR1B1SMN1; SMN2GAA | |
| SCHEMBL11259354 | 0.81 | L3MBTL1 (0.63) | L3MBTL1FFAR1RORCFFAR4RAB9A | |
| SCHEMBL11346344 | 0.81 | L3MBTL1 (0.63) | L3MBTL1FFAR1RORCFFAR4RAB9A | |
| SCHEMBL3841167 | 0.80 | POLB (0.57) | FFAR1AKR1B1FFAR4RAB9AGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070010526-A1 | Therapeutic isoquinoline compounds | ASTRAZENECA AB (SE) | 2007-01-11 | — | — | US | disclosed |
| EP-1451172-A1 | THERAPEUTIC ISOQUINOLINE COMPOUNDS | AstraZeneca AB (SE) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003037887-A1 | THERAPEUTIC ISOQUINOLINE COMPOUNDS | ASTRAZENECA AB (SE) | 2003-05-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010526-A1 | Therapeutic isoquinoline compounds | HTR1B, HTR1D, HTR1A | L3MBTL1 3948/4885FFAR1 1385/4885AKR1B1 1913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.